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Flashcards in PPROM COPY Deck (12)
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1

What is the incidence of PPROM?

3%

RCOG

2

PPROM is associated with _______ of preterm births

30-40%

RCOG

3

What is the median latency after PPROM?

7 days

RCOG

4

What are the benefits of erythromycin in the context of PPROM?

Reduced Chorioamnionitis
Prolonged latency
Improved neonatal outcomes

RCOG

5

Is tocolysis recommended in PPROM?

No

Cochrane review found that
- tocolysis does not significantly improve perinatal outcome and might be associated with an increased risk of chorioamnionitis
- tocolysis was associated with an increased risk of APGAR <7 and the need for ventilation support

6

With PPROM, what is the delivery latency from

24-28/40
31/40

24-28/40: 8-10 days

31/40: 5 days

7

With PPROM, what are three risk factors for complications
(Fetal death, placental abruption, umbilical cord prolapse, delivery outside of hospital, neonatal death)

PPROM <26/40
Non-cephalic presentation
Oligohydramnios

8

What does Amnisure test for?

Placental Micro Globulin PAMG-1

9

What are the complications of PPROM?

Prematurity
Sepsis (Chorioamnionitis)
Cord prolapse
Placental abruption
Pulmonary hypoplasia

10

Why is increased emotional support required in PPROM?

Increased rate of PTSD

11

What were the findings of the Cochrane review on amnio infusion with PPROM?

Associated with improved outcomes in
- fetal umbilical artery pH at delivery
- variable decelerations in labour
- neonatal death
- neonatal sepsis
- pulmonary hypoplasia
- puerperal sepsis

BUT insufficient data: further evidence required.
NOT currently recommended as part of routine clinical practice

12

What antibiotic should be used in PPROM, if a woman is allergic to erythromycin?

Penicillin

(NICE guideline)