Premalignant Lesions

Question 1

Causes of white patches?

Answer 1

Normal anatomy

Developmental

Traumatic

Chemical

Autoimmune

Infective

Question 2

Clinical features of oral hairy leukoplakia?

Answer 2

Painless

May mimic other oral mucosal diseases

Not premalignant

Question 3

How is oral hairy leukoplakia treated if associated with AIDS?

Answer 3

With HAART

Question 4

Clinical features of leukoplakia suggestive of increased risk of malignant transformation?

Answer 4

Surface:
- Raised/nodular

Colour:
- Red/white (speckled)

Site:
- Floor of mouth
- Lateral border of tongue
- Retromolar region
- Buccal sulcus (paan chewers)
- Labial commissure

Advanced age

Female gender

Question 5

Aetiology of leukoplakia?

Answer 5

Tobacco
- Chewing tobacco - paan
- Reverse smoking
- Pipe smoking

Smokeless tobacco & oral epithelial dysplasia

C. albicans

Question 6

Which lesions are always high risk?

Answer 6

All red patches (erythroplakias)

Non-homogenous leukoplakias - i.e. speckled or nodular appearance

All lesions showing dysplasia