Primary Sclerosing Cholangitis Flashcards by David Adey

Q

What other bowel disease is associated with PSC?

A

Ulcerative colitis

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Q

What are the risk factors for PSC?

A

Male

30-40 years old

Ulcerative colitis

Family history

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Q

What is the presentation of PSC?

A

Jaundice

Chronic RUQ pain

Pruritis

Fatigue

Hepatomegaly

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Q

What is the most deranged liver enzyme in PSC?

A

ALP

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Q

What is the primary autoantibody found in PSC?

A

Antineutrophil cytoplasmic antibody (p-ANCA)

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Q

What is the gold standard tool for diagnosing PSC?

A

MRCP

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Q

What are the complications of PSC?

A

Acute bacterial cholangitis

Cholangiocarcinoma

Colorectal cancer

Cirrhosis

Biliary strictures

Fat soluble vitamins deficiency

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Q

What is the management of PSC?

A

Liver transplant

ERCP

Ursodeoxycholic acid

Colestyramine

Monitoring complications

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