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Endocrinology > principles of endocrinology > Flashcards

Flashcards in principles of endocrinology Deck (17):
1

what type of signaling is when hormones are synthesized by endocrine cells and are secreted into blood stream and have their systemic effects

endocrine signaling

2

which hormone circulates in free form and binds to surface receptors?

peptide hormones

3

which hormones are derived from cholesterol

steroid hormones

4

which hormones bind to intracellular receptors

steroid hormones

5

which hormone is derived from tyrosine?

amino acid hormones

6

what are peptide hormones composed of

multiple amino acids

7

what do amino acid horomones produce

catecholamine and thyroid hormones

8

which hormones have longer 1/2 life? why?

lipophilic hormones have longer half life than water soluble, because lipophilic hormones bind to plasma protein which increase 1/2 life.

the more plasma protein binding, the longer the 1/2 life

9

What mechanisms regulates the hormone release?

neural, hormonal, nutrient/ion regulation

10

what are the causes of endocrine dysfunction?

too much or too little hormone action, decreased responsive ness, decreased sensitivity

11

if you have high pituitary hormone level and low target hormone level, the cause is?

failure of target organ

12

if you have low pit, hormone level and low target hormone level.. it's due to?

pituitary failure

13

High pituitary hormone level and high target hormone level

autonomous secretion of pituitary hormone or resistance to target hormone action.

neg feedback not working due to defect on pituitary, or if target organ is not responding to hormone will cause pituitary to produce more

14

Low pituitary hormone level and high target hormone level

autonomous secretion by target endocrine organ

15

Physiological "add back"

supplement hormone if lack endogenous hormones, ie hypogonadism

16

stimulation test

oral glucose to test insulin release

17

suppression test

dexamethasone to test negative feedback on ACTH release from pituitary