Flashcards in principles of reproduction Deck (41):
which cells produce/secrete testosterone in the blood
what are the key functions of sertoli cells
support germ cells, signal spermatogenesis, regulate pituitary function
what cell produce androgen binding protein
what is the key regulator of testosterone production in leydig cells
what is the key regulator of Serotoli cell proliferation and seminiferoutubule growth
which hormone regulates pulsatile release of gonadotropin?
inhibin B is produced by what cell?
sertoli cells in resposne to FSH
what hormone blocks effects of inhibin B
what proteins do testosterone bound to, and in what form do they have to convert to in order for appropriate binding for the diff receptors?
sex hormone binding globulin
Conversion to DHT andAndrogen-binding protein(from serotoli cells)
Convert to estradiol and bind to estrogen receptors
DHT hormone function
sexual develop't, pubic and underarm hair developt, activity of sebaceous glands
estradiol hormone function
epiphyseal closure, suppress osteoporosis, feedback regulation at hypothalamus
which hormone has anabolic effects in muscle/bone
which hormone form secondary sex characteristics?
maturation of spermatids
Maturation of spermatid consists of what
nuclear condensing, formation of acrosome, positioning for tail formation
release of spermatid from sertoli cells into lumen
how long is the process of spermatogonia to spermatoza
what hormone promotes initation and maintenace of spermatogenesis
what two testosterone are needed for complete maturation of spermatozoa?
FSH and testosterone
what does the follicle consist of?
internal granulosa cells and "external" theca cells
Follicular phase (day 1-ovulation)
follicular phase is followed by ovulation
-corpus luteum forms temporary endocrine gland to secrete estradiol and progesterone via
-followed by menses
-endocrine function (estradiol and progesterone)
what does the theca and granulosa cell synthesize and secrete during ovarian cycle
progesterone, androgen, estrogen
what does the follicle produce in follicular phase?
estradiol and inhibin (esp inhibin B in the beginning)
what controls estradiol production
FSH and LH
what does a rise in estradiol produce in order for follicle developt
low amp, high frequency LH secretion
what is required and induces ovulation
estradiol positive feedback causing surge in LH**
what regulates LH and FSH secretion
how is estradiol produced during follicular phase
in response to LH--->theca cells-->androstenedione-->convert to estradiol in granulosa cells controled by FSH
What marks OVULATION?
INCREASE in Basal body temp because progesterone is thermogenic and will produce an increase in BBT
what regulates gonadotropin release
inhibin B feedback
what causes a decrease in LH release during luteal phase
rise in progesterone--negative feedback
what does the spike in Inhibin B indicate
turning off ovulation process
what is the role of Inhibin A
brings LH and FSH back down to lower levels
when is prostaglandin production present
in which phase does estrogen and progesterone decline? and what response does this cause?
in menstrual phase, result release of proteolytic enzymes that cause lysis of tissue and an increase of prostgladndin production
what hormone replaces LH during implantation
Progesterone role during implantation
suppress uterin contraction by inhibiting prostaglandin production and aids immune response
estrogen role during implantation
stimulate uterine, mammary, and vaginal epithelium growth
when does the frequency of LH secretion decrease? why?
Luteal phase, due to negative feedback of progesterone