Prototype Drug Unit 6- Amiodarone

Question 1

Therapeutic classification

Answer 1

Antidysrhythmic, Class 3

Question 2

Pharmacologic classification

Answer 2

Potassium channel blocker

Question 3

Therapeutic effects and uses

Answer 3

It is used as a broad-spectrum antidysrhythmic because it works for treating against atrial and ventricular dysrhythmias.

Also approved for resistant ventricular tachycardia

Question 4

Mechanism of action

Answer 4

Not known

Question 5

Adverse effects

Answer 5

Nausea, vomiting, anorexia, fatigue, dizziness, hypotension, visual disturbances, rashes.

Can have photosensitivity!

Question 6

Black box warning (oral form only)

Answer 6

Causes a pneumonia like syndrome in the lungs.

Baseline lung function test is essential!

Question 7

Contraindications

Answer 7

Hypersensitivity
Hypokalemia and hypomagnesisemia should be corrected before treatment.
People with respiratory problems

Question 8

Drug interactions

Answer 8

Digoxin= levels can rise by 70%
Anticoagulants= dose should be cut in half
Beta blockers and CCB= sinus bradycardia, sinus arrest, or AV block

Question 9

Herbal/food interactions

Answer 9

Echinacea= increases liver toxicity

Grapefruit juice= increases serious level by 80%