PSL301: Cardio 8 Flashcards Preview

PSL301 > PSL301: Cardio 8 > Flashcards

Flashcards in PSL301: Cardio 8 Deck (44):
1

Pc

capillary hydrostatic pressure

2

Pif

interstitial fluid pressure

3

(pi)c

plasma colloid osmotic pressure

4

(pi)if

Interstitial fluid colloid pressure

5

Define: Pc

move fluid out
due to fluid pressure in blood

6

Define: Pif

move fluid in
Opposes outward movement of Pc
due to fluid pressure in ISF

7

Define: (pi)c

Move fluid in
if proteins in blood > proteins in ISF

8

Define: (pi)if

Move fluid out
if proteins in ISF > proteins in blood

9

Formula: net fluid pressure (at capillaries)

Fluid out - fluid in
[Pc + (pi)if] - [Pif + (pi)c]

10

Value: Pif
why?

- 3 mmHg
Lymphatic system remove fluid

11

Value: Pc

45 to 10 mmHg

12

Value: (pi)if
why?

8 mmHg
Lympathic system remove proteins

13

Value: (pi)c

28 mmHg

14

Value: plasma protein concentration

7.3 mg/dl

15

What makes up the plasma proteins?

75% albumin
25% globulin
Very little fibrinogen

16

Value: interstitial protein concentration

3 mg/dl

17

If net fluid pressure is positive...

More fluid going out of vessel

18

If net fluid pressure is negative...

More fluid going into vessel

19

Due to the gradient from Pc, __L of net flow outward per day

3L

20

Forces that push fluid out of vessels

1. Hydrostatic pressure
2. Pressure from LACK OF fluid in ISF
3. Interstitial colloid osmotic pressure

21

Forces that push fluid into vessels

1. plasma colloid osmotic pressure

22

Value: mean hydrostatic pressure

17.3 mmHg

23

Value: filtration coefficient

10 mL/min/mmHg

24

Formula: filtration rate

filtration coefficient * net filtration pressure

25

Value: net filtration rate

3 mL/min
that much fluid is deposited in ISF every minute

26

Functions of lympathic system

1. Return fluid & proteins to circulatory system
2. Pick up fat from intestines and deliver to circulatory system
3. Help trap pathogens

27

Lymphatic system help prevent...

edema

28

Lymph is derived from...

ISF

29

Where does the lymphatic system drain into?

subclavian veins

30

What determines lymph flow?

1. Valves
2. External compression (skeletal pump)
3. Smooth muscle in lymph vessel
4. Pif

31

What if flow in lymphatic system is blocked?

Edema

32

3 factors that might cause edema

1. Increase hydrostatic pressure
2. Decrease in plasma protein
3. Increase in interstitial proteins

33

Where does edema happen?

any vascularized tissue

34

One specific edema disease is...

Elephantiasis

35

What causes elephantiasis?

small parasitic roundworms

36

What is the vector for elephantiasis?

Mosquitos

37

Define: elephantiasis

abnormal enlargement of any part of the body due to obstruction of the lymphatic channels in the area

38

Fluid accumulation in the abdomen is called...

Ascites

39

Ascites

Accumulation of fluid in the abdomen

40

Another name for abdomin

peritoneal cavity

41

Disease of ascites

Kwashiorkor: lack of protein in diet
Liver cirrhosis: cannot produce enough albumin

42

What may cause liver cirrhosis?

Alcoholism
Hepatitis
Fatty liver disease
Acetaminophen

43

CVD includes...

1. CHD
2. Cerebrovascular disease
3. Peripheral arterial disease
4. Rheumatic heart disease
5. Congenital heart disease
6. Deep vein thrombosis & pulmonary embolism

44

Rheumatic heart disease is caused by...

Streptococcus pyogenes infection -> Rheumatic fever