Psychiatry

Question 1

• What psychiatric drug is associated with agranulocytosis?

- What is this drug used to treat and what is its mechanism of action?

Answer 1

-clozapine-serotonin+dopamine antagonist used to treat schizophrenia

Question 2

• What type of foods should be avoided in patients taking MAOIs?
• Why?
• give some examples of MAOIs

Answer 2

• Cheese, alcohol, beef, chicken liver, chocolate
• these foods have tyramine in them which can react with the MAOI to cause life threatening elevations in noradrenaline
• Tranylcypromine (Parnate), phenelzine (Nardil) and isocarboxazid