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Exam 8 > Psychosis > Flashcards

Flashcards in Psychosis Deck (37):
1

False perceptions

Hallucination

2

False beliefs

Delusion

3

Gross disturbances in comprehension of reality, false perceptions, and false beliefs

Psychosis

4

Caused by abnormalities in _________ transmission in mesolimbic and mesocortical pathways

dopamine

5

Drugs that block __________ receptor improve psychosis

D2

6

Affinity at _________ receptor associated with clinical efficacy of antipsychotics

D2

7

Drugs that increase ________ release (such as ___________) or block reuptake (such as _____) induce psychotic behavior

dopamine
amphetamine
cocaine

8

Responsible for extrapyramidal side effects of psychosis

nigrostriatal

9

Changes to nigrostriatal in psychosis?

None

10

Negative and cognitive sxs

DLPFC

11

Negative and affective symptoms

VMPFC

12

Changes in tuberoinfundibular tract in psychosis?

None

13

Associated with prolactin related side effects of antipsychotics

Tuberoinfundibular tract

14

Psychosis two types
____ disorders or _____ disorders

Affective
Manic depressive

15

Positive sxs respond well to

neuroleptics (typical antipsychotics)

16

More difficult to treat and often persist after positive sxs resolve

negative sxs

17

Positive or negative sxs associated with a poorer prognosis

Negative

18

Phenothiazines, thioxanthenes, butyrophenones, azepines, dihydroindolone

Typical antipsychotics

19

Azepines, benzisoxazole, benzisothiazolylpiperzine

Atypical antipsychotics

20

Chlorpromazine, fluphenazine, thioridazine, trifluoperazine, mesoridazine, perphenazine

Phenothiazines
Typical antipsychotics

21

Thiothixene and chlorprothixene

Thioxanthenes
Typical antipsychotics

22

Haloperidol, sciperone

Butyrophenones
Typical antipsychotics

23

Loxapine

Azepines
Typical antipsychotics

24

Molindone

Dihydroindolone
Typical antipsychotics

25

Clozapine, olanzapine, quetiapine

Azepines
Atypical antipsychotics

26

Risperidone
Aripiprazole

Benzisoxazole
Atypical antipsychotics

27

Ziprasidone

Benzisothiazolylpiperzine
Atypical antipsychotics

28

Antipsychotic drugs block __________ and __________ receptors

dopamine
serotonin

29

Adverse effects of ____________ are contribute to blockage of alpha 1, histamine, and muscarinic receptors

antipsychotics

30

More likely to be effective in drug refractory pts

Atypical antipsychotics

31

______________ sxs subside 1-3 wks after treatment is initiated

positive

32

Spontaneous movement and behavior is suppressed with

antipsychotics

33

No motor incoordination at usual doses of

antipsychotics

34

D2 receptors are

G protein coupled receptors
Gi or Go

35

Decreased agitation, aggression, and anxiety. Normalization of eating and sleeping patterns ____ after treatment

1-3 days

36

Increased socialization, self care, and mood ____ after treatment

1-2 weeks

37

Increased thought disorder and decreased delusions/hallucinations. Appropriate conversations _____ after treatment

3-6 weeks