Pulm - interstitial Lung Disease Solitary Nodule & Sarcoid Flashcards Preview

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Flashcards in Pulm - interstitial Lung Disease Solitary Nodule & Sarcoid Deck (12):
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When to get a biopsy of a solitary pulmonary nodule?

HPI: smoker over 40
PE: lymphadenopathy
Imaging: enlarging large (greater than sign 2 cm) spiculated, with sparse eccentric calcifications and abnormal PET scan

1

Patient with intermediate probability of malignancy on solitary pulmonary nodule – most appropriate next step?

If cytology is positive?

Bronchoscopy or transthoracic needle biopsy

Resection with positive sputum cytology

2

Drugs that cause pulmonary fibrosis?

#Bleomycin
#Amiodarone
#nitrofurantoin
#Cyclophosphamide
#Busulfan
#Methylsergide

3

Pneumoconiosis if exposed to:
1. Sandblasting, rock mining
2. Cotton
3. Electronic manufacture
4. Moldy sugarcane

1. Silicosis
2. Byssinosis
3. Beryllosis
4. Bagassosis

4

All types of pulmonary fibrosis presents with?

#Dyspnea
#Crackles/Rales
#Loud P2
#Clubbing

5

Best initial test if suspecting fibrosis?

Most accurate test?

Chest x-ray

Biopsy

6

Pneumoconiosis in which biopsy will show granulomas?

Berylliosis

7

Patient with suspected interstitial lung disease – biopsy finding that indicates reversibility? Permanence?

Inflammatory infiltrate with white blood cells

Fibrosis

8

If biopsy of patient with interstitial lung disease shows WBC infiltrate – management?

Steroids

9

Typical presentation of sarcoid?

Young African-American woman with:
1) shortness of breath, and rales without wheezing
2) erythema nodosum
3) lymphadenopathy

10

Other, less common findings in sarcoidosis?

#Parotid gland enlargement
#Facial palsy
#Heart block with restrictive cardiomyopathy
#CNS involvement
#Uveitis

11

Lab abnormalities in sarcoidosis?

#Elevated ACE
#Hypercalciuria
#Hypercalcemia

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