Pulmonary blood flow, VQ Flashcards Preview

Physiology > Pulmonary blood flow, VQ > Flashcards

Flashcards in Pulmonary blood flow, VQ Deck (7)
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1
Q

What regulates pulmonary blood flow

A

Resistance of arterioles mediated by local vasoactive substances

2
Q

major factor that regulates pulmonary blood flow

A

PA.O2- alveolar

3
Q

Hypoxic vasoconstriction

A

Adaptation that reduces blood flow to poorly ventilated regions of the lung-good, decreases PAO2

4
Q

When is hypoxic vasoconstriction not a good adaptation

A

in severe lung disease (multi-lobar pneumonia) reduced blood flow to poorly ventilated areas causes hypoxemia

5
Q

What is the role of NO

A

potent vasodilator

6
Q

which vasoactive substances does the cycooxygenase pathway produce

A
  • Thromboxane (vasoconstriction)

* Prostacyclin (vasodilation)

7
Q

What vasoactive substance does lipoxygenase pathway produce

A

Leukotrienes (vasoconstriction of blood vessels and airways)