Q 3: Scotchguard Flashcards Preview

Y2 T1 Toxicology 200 > Q 3: Scotchguard > Flashcards

Flashcards in Q 3: Scotchguard Deck (10)
1

Risk-Benefit

Most resources we use come with a risk, yet the benefit is enough to ignore.

2

PFO

Perfluorinated chemicals

3

The Janus affect

yin and yang- two sided aspects

4

PCB example

electric tranfusors

5

Chloro-fluorocarbons ex

killer refrigerator

6

Perfluoroctane sulfonate

-very persistent, doesn't break down
-Banned Globally
-PFOS
-Can't be metabolized by animals or bacteria
-doesnt fertilize(break down in light)
PFOS is a fatty acid analogue
Not metabolized
Amphiphilic
Terminal degradation product of many chemicals
Preferentially retained in plasma and liver
binds to protein
Affects membranes
-Fatty acid analog, seen by body as naturally occurring
- does very well in blocking water and grease
-bind to proteins not fat like others
- Utilized to coat paper and packaging in PFOS wax
- Microwave popcorn had it in paper


7

Major uses of PFOS in _____ and ______.

Carpeting and Microchips

8

___% of PFOS was leaked from carpet

10

9

Mechanisms of dispersion

Methyl- and Ethyl-FOSE alcohols are more volatile and likely moved in atmosphere
Released during manufacture as well as 1-3% residual in products
Accumulated into aquatic organisms and into predators and transformed into PFOS

10

What needed to be done?

Develop and validate analytical methods
Conduct global survey
Determine Critical Mechanism of Toxic Action
Conduct Global Risk Assessment
Present Information to Regulators
All of this was done within one year