Flashcards in Q3 Deck (15):
T/F: Tetrodotoxin is derived from the puffer fish an is highly specific to Na channels.
4-Aminopyridine (4-AP) is a highly specific blocker of what ion channels?
T/F: Ionic pumps maintain the intracellular Na concentration at a high value and K concentration at a low value.
Mechanical trauma can damage nerve membranes and their proteins, making them more what to ions?
What clamp (current or voltage) makes it possible to study currents through single ion channels?
T/F: Conductances are calculated, not measured.
At any level of depolarization, which ionic current precedes K current?
About 40% of which HH channels are inactivated at teh normal resting potetnial of -65mV?
Does hyperpolarization remove inactivation with time?
Cooling a preparation has what effect on ion channel conductance kinetics?
Reduces the conductance and current.
Warming a preparation has what effect on ion channel conductance kinetics?
Increases the conductance and current.
What controls many processes fundamental to a living organism?
Neher and Sakmann invented which technique in 1976?
To observe single Na and K channels, what type of patch is used?