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Flashcards in QUESTIONS Deck (43):
1

The transport of a drug in body fluids from the bloodstream to various tissues of the body and ultimately to its site of action is termed:

Distribution

2

A drug or substance that blocks the receptor sites on the cell membrane and prevents the normal physiologic function is termed a/an:

Antagonist

3

Which of the following dosage forms is normally associated with the highest speed of absorption into the body?

Solutions

4

Various types of tablets have a special enteric coating to enable the:

drugs passage through the highly acidic stomach

5

All of the following are involved in the pharmacokinetic process except:

antagonist

6

The antagonist is not involved in the _____ process

pharmacokinetics

7

Drugs that are administered orally generally travel first to the liver before entering the general circulation. This is referred to as:

first-pass metabolism

8

Which of the following contains sodium bicarbonate and an organic acid?

Effervescent

9

The process by which any solid/semi-solid substance enters the solvent to yield a solution where the drug must first enter one of the dosage forms before being absorbed is called:

Dissolution

10

If the physician is monitoring how long it will take after a patient administers his/her medication until he/she sees or feels the first sign of its effects; then the physician is concerned with the drugs:

onset of action and latent period

11

Drugs that have a strong affinity for a receptor, will allow a drug to elicit a/an _____ effect:
A. Antagonist and mixed agonist
B. Agonist
C. Antagonist
D. All of the above

D. All of the above

12

A solid drug dispersed in a liquid medium that requires shaking before administering is referred to as:

suspension

13

Mr. Woodward takes an antihistamine and reports that it has a mild, calming effect on him. The physician tells him that this is not unusual and it is considered a predictable action on the body. The antianxiety effect on this drug is called a:

Side effect

14

When a drug is transformed from a liquid-soluble substance to a water-soluble substance for excretion it is referred to as:

Conjugation

15

______ is concerned with the method for achieving effective drug administration?

Biopharmaceutics

16

Mr. Steroid takes a drug that results in a very uncomfortable immune-mediated response by the body against the drug that does not seem related to dose. Mr. Steroid has experienced a/an:

allergic reaction

17

Kanye West is taking a new medication in addition to others he has used for years. This new medication is fairly effective, but it has the ability to interfere with the action of other drugs that have greater efficacy. Mr. West's new medication is acting as a:

partial agonist

18

Factors that contribute to prolonged drug metabolism include:

liver disease, immature metabolizing enzyme systems, and renal problems.

19

A _____ is the term for specific biologic sites located on the cell surface or within a cell.

receptor

20

If a physician is looking for the highest plasma concentration attained from a dose of a specific drug, then the physician is looking for its:

peak serum concentration

21

Oxygen, anesthetics, and inhalers are examples of:

gas dosage forms

22

Which statement is true regarding lipophilicity:

water soluble drugs will not cross the cell membrane

23

The degree to which a pharmaceutical is able to produce the desired effect (how great the effect will be) in the target tissue is known as the drugs:

efficacy

24

The study o the effect of a drug on the body and its manifestations is termed:

Pharmacodynamics

25

The suppository may be administered in which of the following ways:

vaginally/rectally

26

The ABSORPTION properties that affect the rate at which a pharmaceutical reaches the site of action depends on all of the following except:

the number of functional cells in the organ of interest

27

Weak acids are able to cross barriers best when it is:

in a acid medium

28

The human cell membrane is normally composed of a:

double layer of lipids

29

While studying a new medication, the research team discovered the drugs plasma concentrations that produce the desired effect without toxicity. The team was able to discover the drugs:

therapeutic range

30

A patient is prescribed an oral medication whose active ingredient is not released until the medicine reaches the small intestine. The form of medication prevents the acidic contents of the stomach from destroying the drugs activity.

enteric-coated tablet

31

The mechanism by which drugs produce their desired effect includes all of the following except

Drug-protein interactions

32

With regards to acid-base properties:

neutral particles cross membranes better than ionized particles and nonionized particles cross better that ionized particles

33

Dosage forms:

Solid
Liquid
Gas
Or any combo of these

34

Lebron James takes two drugs at the same time. His physician determines that if the two drugs interact with each other, they may produce addictive ______ responses:
A. Agonist
B. Synergistic
C. Antagonist
D. ALL OF THE ABOVE

D. ALL OF THE ABOVE

35

A new medication is developed that consists of two immiscible liquids. One liquid appears as globules uniformly dispersed throughout the other liquid. What is most likely to be used to maintain globule stability?

Emulsifying agent

36

The time required for a dosage form to break up into granules of smaller size under specified conditions is termed:

Disintegration

37

All of the following are factors affecting drugs distribution except:

time of day the medication is administered

38

Troches are:
A. Solids containing medicine in a hard candy
B. Dissolves slowly in the mouth
C. Includes lozenges and pastilles
D. ALL of the above

D. ALL of the above

39

All of the following are true regarding blood-brain barriers (BBB) except:

small molecules do not pass through the blood brain barrier easily

40

A patient is suffering from bronchospasms and is given the drug epinephrine. The drug works to stimulate or enhance the bodies natural physiologic function, and no new function is developed. Epinephrine has a/an _____ effect.

Agonist

41

This is the most common way by which drugs cross membranes:

Passive transport

42

When a drug needs a carrier molecule to assist with its movement in the cell across a concentration barrier it is classified as a form of:

active transport

43

A patient is given a solution form that reacts with the body by moving from an area of high concentration to an area of low concentration. Which of the following is true?

The drug is traversing cellular membranes by passive diffusion