Quiz 1

Question 1

All the following are characteristics of acute-phase reactants EXCEPT:

-they limit destruction of host tissue
-they are constituents that increase rapidly in response to infection
-they enhance phagocytosis
-they are used to diagnose a specific disease

Answer 1

they are used to diagnose a specific disease

Question 2

the test that could be used to determine whether a patient has a specific deficiency in C3.s

Answer 2

Radial immunodiffusion

Question 3

Which of the following can activate the alternative complement pathway?
-IgG
-C1q
-mannose-binding lectin
-C3b

Answer 3

C3b

Question 4

Which of the following is a characteristic of opsonins?
-They are expressed on the surface of neutrophils
-They are molecules that coat bacteria, making them more susceptible to phagocytosis
-They are produced by NK cells
-They are carbohydrates that stimulate T cells

Answer 4

-They are molecules that coat bacteria, making them more susceptible to phagocytosis

Question 5

Where does the specific immune response to foreign antigen mainly occur?

Answer 5

-Lymph nodes

Question 6

most likely sites where specific immune responses develop against bacteria causing a skin infection?

Answer 6

-Lymph nodes

Question 7

All the following cell types can present antigen to T helper cells, EXCEPT:
-monocyte
-macrophage
-dendritic cell
-neutrophil

Answer 7

-neutrophil

Question 8

All the following are characteristics of a strong immunogen EXCEPT:
-it is a large molecule
-it is protein in nature
-it is a repeating polymer
-it is foreign to the host

Answer 8

-it is a repeating polymer

Question 9

A macromolecule that is capable of eliciting an immune response in an immunocompetent individual is called:

Answer 9

-an antigen

Question 10

Which of the following is characteristic of natural immunity?
-T lymphocytes play a major role
-It involves memory
-it involves specificity
-mechanisms are always present and fully functional

Answer 10

mechanisms are always present and fully functional

Question 11

Which complement components has chemotactic activity?

Answer 11

C3a

Question 12

the condition that could result from a deficiency in complement C2.

Answer 12

Immune complex disease

Question 13

What is cleaved by C3bBb?

Answer 13

C3

Question 14

Which type of cell has a diameter between 10 and 15 micrometers, has a multi-lobed nucleus, and usually comprises more than 50% of circulating leukocytes?

Answer 14

-Neutrophil

Question 15

Antibodies are secreted by:

Answer 15

plasma cells

Question 16

Which of the following is a characteristic of natural killer cells?
-They are a type of lymphocyte
-They are part of the adaptive immune system
-They are smaller than B and T cells
-They mature in the thymus

Answer 16

They are a type of lymphocyte

Question 17

What is a low-molecular-weight molecule that has one binding site for an antibody?

Answer 17

Hapten

Question 18

An antigenic determinant is also called:

Answer 18

-an epitope

Question 19

Hematopoietic stem cells are located in the:

Answer 19

-bone marrow

Question 20

Which white cell in the peripheral blood migrates into tissue to become a macrophage?

Answer 20

-Monocyte

Question 21

Which of the following is NOT a component or characteristic of natural (innate) immunity?

-Repeated exposure to a pathogen does not change the response
-The response involves phagocytosis
-The response involves acute-phase reactants
-The response involves antibodies

Answer 21

-The response involves antibodies

Question 22

A substance that is too small to stimulate antibody production by itself unless it is attached to a larger carrier molecule is called:

Answer 22

a hapten

Question 23

The anaphylotoxins are produced by proteolytic cleavage of:

Answer 23

C5 and C3

Question 24

T cells mature in the:

Answer 24

thymus

Question 25

Contact with antigen and activation of B cells normally occurs in the:

Answer 25

-lymph nodes

Question 26

Which of the following are components play a role in initiating both innate and adaptive immune responses?

-T helper cells
-B cells
-Immunoglobulins
-Macrophages

Answer 26

-Macrophages

Question 27

A 50-kDa protein from a bacterial cell that has numerous different epitopes would be called:

Answer 27

-an immunogen and an antigen

Question 28

Which of the following would be the most effective immunogen?

-One with a molecular weight of less than 10,000 Da
-One that is genetically foreign and has a single epitope
-One with multiple epitopes with a single repeated specificity
-One with multiple epitopes with many specificities

Answer 28

One with multiple epitopes with many specificities