Quiz 4 Joint Flashcards Preview

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Flashcards in Quiz 4 Joint Deck (55):
1

Most common joint pathology

osteoarthritis

2

x-ray findings osteoarthritis

joint space narrowing
sclerosis
osteophyte
subchondral bone cysts

3

Where are haberdon nodes in osteoarthritis?

DIPS

4

RA spares what?

DIPS

5

Antibodies found in RA?

anti-cintrullinated protein antibodies (anti-CCP)
RF

6

hist of RA

increased lymphocytes and
proliferated synoviocytes

7

RA on x-ray

subluxation deformities
(incomplete separation)

8

triad of RA with splenomegaly and hypersplenism

Felty's syndrome

9

What do you call RA under 16?

JRA or JIA or Still's disease

10

What are the 4 types of seronegative spondyloarthropathies that are seronegative for RF and are characterized by inflammatory arthritis in occurrence with other conditions?

ankylosing spondylitis (AS)
reactive arthritis
psoriatic arthritis (PA)
enteropathic arthritis

11

all of the seronegatives are associated with what gene locus?

HLA-B27

12

What does AS affect?

axial skeleton, especially SI joints

13

bamboo sign on x-ray

AS

14

cause of reactive arthritis

past infection causes immune reaction that cross reacts (?)

15

#1 most common organism to cause reactive arthritis associated with GU infection?

chlamydia

16

What GI infections can cause reactive arthritis?

Shigella
Salmonella
yersinia
Campylobacter

17

triad in reactive arthritis

urethritis
cervicitis
conjunctivitis

18

most common infections leading to reactive arthritis

GI in origin

19

synovitis/sausage toe

seen in reactive arthritis

20

lesions on palms and feet (keratosomething)

reactive arthritis

21

non-reactive arthritis associated with IBD and following a bowel infxn of salmonella, shigella, yersinia, or campylobacter

enteropathic arthritis

22

psoriatic arthritis affects what?

DIPS

23

pitting and onycholysis of nails is seen in?

psoriatic arthritis

24

#1 and #2 bugs to cause septic arthritis

staph
strep

25

what causes septic spinal arthritis and what is it called?

TB can cause
called Potts

26

Lyme arthritis caused by what and what is vector?

borrelia burgdorferi

27

most common cause of bacterial or supperative arthritis in adults and older children

#1 Staph
#2 strep

28

most common cause of bacterial arthritis in elderly, IV drug users, and the seriously ill?

e. coli

29

In cases of non-gonococcal arthritis is it common for single or multiple joints to be involved

non-gonoccocal: single
gonococcal: multiple

30

how is TB arthritis spread to the joint?

spread to joint via adjacent TB osteomyelitis or hematogenous spread of pulmonary TB

31

what does TB arthritis affect?

hips, knees, ankles (weight bearing joints)

32

What is TB of the spine?

Pott's disease
affects T and L spine

33

lyme arthritis caused by what?

spirochete: borrelia burgdorferi

34

lyme involved joints

knees, ankles, shoulders, elbows

35

lyme vector

deer tick (ixodes)

36

what type of stain shows spirochetes?

silver stain

37

What viruses can cause viral arthritis?

Hep B and C, HIV, Parvo B19, rubella

38

gout vs pseudogout

gout: monosodium urate crystals
pseudogout: calcium pyrophosphate crystals

39

what can develop as a result of increased uric acid production or decreased uric acid excretion?

hyperuricemia

40

what drugs should you not take with gout?

aspirin, thiazide diuretics, loop diuretics

41

saturnine gout?

from moonshine with lead

42

what is pathognomonic for gout?

tophus

43

Is gout or pseudogout birefringent?

both

44

histology of gout

needle like crystals surrounded by inflammatory and giant multinucleated cells

45

hist of pseudogout

rhomboidal, intracellular crystal

46

ganglionic cysts

lack true cell lining
fluid doesn't communicate with joint space

47

synovial cyst

- fluid does communicate with joint space
- herniation of synovial fluid through joint tissue
- also called bakers cyst

48

Bakers/Synovial cysts can be a complication of what?

RA

49

several, closely related, benign neoplasms that can develop in synovial linings of joints, tendon sheets, and bursae

villonodular synovitis

50

most common types of villonodular synovitis

pigmented villonodular synovitis (PVNS) and diffuse-type giant cel tumor of tendon sheet (GCTTS)

51

what makes villonodular synovitis stain pink?

hemosiderin

52

malignant synovioma

synovial sarcoma
knee, ankle in young adults

53

What antigens is RA associated with?

Class II antigens such as HLA-DR4

54

In what population is N gonorrhoea most commonly seen in bacterial arthritis?

young adults

55

where do you see keratoderma blenorrhagica?

characteristic rash of reactive arthritis