Flashcards in Quiz 4 Joint Deck (55):
Most common joint pathology
x-ray findings osteoarthritis
joint space narrowing
subchondral bone cysts
Where are haberdon nodes in osteoarthritis?
RA spares what?
Antibodies found in RA?
anti-cintrullinated protein antibodies (anti-CCP)
hist of RA
increased lymphocytes and
RA on x-ray
triad of RA with splenomegaly and hypersplenism
What do you call RA under 16?
JRA or JIA or Still's disease
What are the 4 types of seronegative spondyloarthropathies that are seronegative for RF and are characterized by inflammatory arthritis in occurrence with other conditions?
ankylosing spondylitis (AS)
psoriatic arthritis (PA)
all of the seronegatives are associated with what gene locus?
What does AS affect?
axial skeleton, especially SI joints
bamboo sign on x-ray
cause of reactive arthritis
past infection causes immune reaction that cross reacts (?)
#1 most common organism to cause reactive arthritis associated with GU infection?
What GI infections can cause reactive arthritis?
triad in reactive arthritis
most common infections leading to reactive arthritis
GI in origin
seen in reactive arthritis
lesions on palms and feet (keratosomething)
non-reactive arthritis associated with IBD and following a bowel infxn of salmonella, shigella, yersinia, or campylobacter
psoriatic arthritis affects what?
pitting and onycholysis of nails is seen in?
#1 and #2 bugs to cause septic arthritis
what causes septic spinal arthritis and what is it called?
TB can cause
Lyme arthritis caused by what and what is vector?
most common cause of bacterial or supperative arthritis in adults and older children
most common cause of bacterial arthritis in elderly, IV drug users, and the seriously ill?
In cases of non-gonococcal arthritis is it common for single or multiple joints to be involved
how is TB arthritis spread to the joint?
spread to joint via adjacent TB osteomyelitis or hematogenous spread of pulmonary TB
what does TB arthritis affect?
hips, knees, ankles (weight bearing joints)
What is TB of the spine?
affects T and L spine
lyme arthritis caused by what?
spirochete: borrelia burgdorferi
lyme involved joints
knees, ankles, shoulders, elbows
deer tick (ixodes)
what type of stain shows spirochetes?
What viruses can cause viral arthritis?
Hep B and C, HIV, Parvo B19, rubella
gout vs pseudogout
gout: monosodium urate crystals
pseudogout: calcium pyrophosphate crystals
what can develop as a result of increased uric acid production or decreased uric acid excretion?
what drugs should you not take with gout?
aspirin, thiazide diuretics, loop diuretics
from moonshine with lead
what is pathognomonic for gout?
Is gout or pseudogout birefringent?
histology of gout
needle like crystals surrounded by inflammatory and giant multinucleated cells
hist of pseudogout
rhomboidal, intracellular crystal
lack true cell lining
fluid doesn't communicate with joint space
- fluid does communicate with joint space
- herniation of synovial fluid through joint tissue
- also called bakers cyst
Bakers/Synovial cysts can be a complication of what?
several, closely related, benign neoplasms that can develop in synovial linings of joints, tendon sheets, and bursae
most common types of villonodular synovitis
pigmented villonodular synovitis (PVNS) and diffuse-type giant cel tumor of tendon sheet (GCTTS)
what makes villonodular synovitis stain pink?
knee, ankle in young adults
What antigens is RA associated with?
Class II antigens such as HLA-DR4
In what population is N gonorrhoea most commonly seen in bacterial arthritis?