Quiz 7 Flashcards Preview

Pharmacology III > Quiz 7 > Flashcards

Flashcards in Quiz 7 Deck (30):
1

What meds can cause insomnia?

1. Quinolone abx
2. SSRIs
3. Decongestants
4. Dopamine agonists
5. Ethanal
6. Oral contraceptives
7. Thyroid meds

2

Non-Benzos for sleep

1. Ambien (Zolpidem)
2. Sonata (Zaleplon)
3. Lunesta (Eszopiclone)

No effect on sleep stages

3

Which non-benzos can you use long-term for sleep?

Lunesta (Eszopiclone) & XR Ambien (Zolpidem)

4

What are the benzos for sleep?

1. Restoril - Temazepam
2. ProSom - Estazolam
3. Dalmane - Flurazepam
4. Doral - Quazepam
5. Halcion - Triazolam

5

Benzo sleep aids affects on stages?

1. Dec. sleep latency
2. Dec. awakenings
3. REM shortened
4. # of REM cycles inc.
5. Sleep time inc.

6

Contraindications to benzo sleep aids?

Obstructive sleep apnea

7

ADRs Rozerem

Melatonin receptor agonist

1. Dec. testosterone
2. Inc. prolactin
3. Dec. libido
4. Disruption of meses

8

OTC Sleep aids

1. Nytol - Diphenhydramine
2. NiteTime Sleep Aid - Doxylamine

Only work if Pt sensitive, can develop tolerance

9

What is the FDA warning with sleep aids?

Anaphylaxis & angioedema

Sleep driving, telephone calls, cooking & eating

10

What drugs should you avoid with epilepsy?

1. Benzos
2. Opiates
3. Antipsychotics
4. Alcohol

11

What are the Eugeroics for sleep apnea & how do they work?

1. Provigil - Modafinil
2. Ritalin - Methylphenidate
3. Dexedrine - Amphetamines

Inc. dopamine levels at synaptic cleft

12

Who shouldn't take Eugeroics?

1. Cardiac Pts
2. HTN - careful
3. Psych Pts
4. Kiddos

13

Tx for cataplexy?

REM sleep-suppressing drugs

NE or SSRIs
1. Venlaxafine
2. Fluoxetine
3. Atomoxetine
4. Sodium oxybate

14

Non- pharm Tx for restless legs

1. Check iron
2. Moderate regular exercise
3. Leg massage w/ pneumatic compression
4. Heat
5. Mental alerting activities at times of rest/boredom
6. Avoid aggravating factors

15

Meds to Tx restless legs

1. Dopamine agonists (Requip, Mirapex)
2. Benzos (Diazepam, Clonazepam)
3. Alpha-2-delta Ca channel ligands (Gabapentin, Pregabalin)

16

What are the dopamine agonists for restless legs?

1. Requip (Ropinirole)
2. Mirapex (Pramipexole)

17

Describe the 3 compartments for fluids

1. Normal distribution btwn ECF & ICF
2. Accumulation w/in interstitial components
3. Accumulation in parts of body where it's not available for exchange btwn compartments

18

Crystalloid IVF

Substance in soln can diffuse through semipermeable membrane
Electrolyte containing soln made to match the biochemical & osmotic features of the plasma

19

Colloids IVF

Soln that contain high molecular wt proteins & electrolytes
Unable to diffuse through normal capillary membranes
-Used for 3rd compartmentalizing
-Salt, sugar & water

20

What are the standard isotonic IVF?

1. 0.9% sodium chloride
2. Lactated ringers

21

What are the standard Hypotonic IVF?

1. 0.45% sodium chloride
2. 5% dextrose solution

22

What are the standard Hypertonic IVF?

1. 3% sodium chloride - needs intense monitoring
2. 5/25% albumin - big pull from intracellular space w/ possible cell damage

23

Sodium & Osmolarity of 0.9% sodium chloride solution?

Na - 154
Osm - 304

24

At what level do you begin correcting for hyponatremia?

<130

25

What are the water soluble vitamins?

1. Thiamine - B1
2. Riboflavin - B2
3. Niacin - B3
4. Calcium pantothenate - B5
5. Pyridoxine - B6
6. Cyanocobalamin - B12
7. Ascorbic acid - C

26

What vitamin plays a big role in neuronal excitability?

Pyridoxine - B6

27

Fat soluble vitamins?

1. Retinol - A
2. Cholecalciferol - D
3. Tocopherol - E
4. Phytonadione - K

28

What does selenium do?

Free radical defense & antioxidative

29

Types of drugs for urinary incontinence

1. Antimuscarinics - Ditropan (Oxybutynin)
2. Adrenergic agonists - Myrbetriq (Mirabegron)
3. Imipramine (Tofranil)
4. Botox

30

Contraindications for Oxybutynin

Antimuscarinic for urinary incontinence

1. Angle-closure glaucoma
2. Gastric retention