Flashcards in R/O - Rheumatic & vasculitis diseases in children Deck (32)
what is JIA (juvenile idiopathic arthritis)?
- hyperplasia of synovial lining
- morning stiffness
- rheumatoid nodules
- limp / refusal to bear weight
- joint edema, erythema, warmth
polyarthritis is arthritis in how many joints?
5 or more
oligoarthritis - what should you look for?
ANA positivity occurs in what type of arthritis?
what joints are affected in polyarthritis?
all large joints
what joints are affected in oligoarthritis?
knees / ankles
Rh factor is (sometimes, 10%) positive in what type of arthritis?
if patient is ANA positive, __________ is more common and therefore requires a ___________ exam
- eye exam
ANA - worry about:
- limited ROM
- increased heat
patient 16 yo or younger
what is the treatment for JIA?
- multidisciplinary team (PCP, social services, PT, rheumo, ophtho, nurse, family)
- NSAIDs (first line)
- immunosuppressive (DMARDs) - delay progress
- joint injections
JIA is worse if positive for:
psoriatic arthritis is arthiritis with 2 or more of:
- nail piting / oncycholysis
- family history of psoriasis
treatment for psoriatic arthritis requires:
what is the enthesis?
site of attachment of muscle or ligament to bone
- SI joint tenderness
- HLA B27 positive
- acute uveitis
- oligo or polyarthritis
boy 8 yo or older
enthesitis related JIA
neonatal lupus is caused by:
maternal transfer of antibodies
what are the symptoms of neonatal lupus?
- hematologic: thrombocytopenia
- cardiac: complete heart block
- liver: hepatomegaly, hepatitis
children with neonatal lupus and cardiac complications require what therapy?****
henoch schonlein purpura is immune mediated via what Ig?
- non thrombocytopenic purpura
- 2-10 yo
what is diagnostic for HSP?
are the palpable purpura from HSP symmetric or asymmetric?
what are a few GI complications from HSP?
what are the renal complications in HSP?
- nephritis (asymptomatic hematuria, possible proteinuria)
- progressive renal failure (rare)
- acute insufficiency (rare)
what is the treatment for HSP?
- steroids (mostly for ab pain)
what is the triad of HUS?
- microangiopathic hemolytic anemia
- renal insufficiency
most cases of HUS are caused by:
shiga toxin producing straings E. coli 0157:H7
- abdominal pain followed by diarrhea that becomes bloody
- possible fever (low grade)
- fatigue, pallor
- edema / HTN
- seizure / coma
what meds should be AVOIDED in HUS?
- platelet transfusions