R/O - Rheumatic & vasculitis diseases in children Flashcards Preview

Year 2 Specialty Medicine > R/O - Rheumatic & vasculitis diseases in children > Flashcards

Flashcards in R/O - Rheumatic & vasculitis diseases in children Deck (32):
1

what is JIA (juvenile idiopathic arthritis)?

- hyperplasia of synovial lining
- edema
- hyperemia

2

- morning stiffness
- rheumatoid nodules
- limp / refusal to bear weight
- deformity
- joint edema, erythema, warmth

JIA

3

polyarthritis is arthritis in how many joints?

5 or more

4

oligoarthritis - what should you look for?

uveitis

5

ANA positivity occurs in what type of arthritis?

oligoarthritis

6

what joints are affected in polyarthritis?

all large joints

7

what joints are affected in oligoarthritis?

knees / ankles

8

Rh factor is (sometimes, 10%) positive in what type of arthritis?

poly

9

if patient is ANA positive, __________ is more common and therefore requires a ___________ exam

- uveitis
- eye exam

10

ANA - worry about:

uveitis

11

- swelling
- limited ROM
- tenderness
- increased heat

patient 16 yo or younger

JIA

12

what is the treatment for JIA?

- multidisciplinary team (PCP, social services, PT, rheumo, ophtho, nurse, family)
- NSAIDs (first line)
- immunosuppressive (DMARDs) - delay progress
- steroids
- joint injections

13

JIA is worse if positive for:

Rh factor

14

psoriatic arthritis is arthiritis with 2 or more of:

- dactylitis
- nail piting / oncycholysis
- family history of psoriasis

15

treatment for psoriatic arthritis requires:

DMARDs

16

what is the enthesis?

site of attachment of muscle or ligament to bone

17

- SI joint tenderness
- HLA B27 positive
- acute uveitis
- oligo or polyarthritis

boy 8 yo or older

enthesitis related JIA

18

neonatal lupus is caused by:

maternal transfer of antibodies

19

what are the symptoms of neonatal lupus?

- hematologic: thrombocytopenia
- cardiac: complete heart block
- liver: hepatomegaly, hepatitis

20

children with neonatal lupus and cardiac complications require what therapy?****

permanent pacemaker

21

henoch schonlein purpura is immune mediated via what Ig?

IgA

22

- non thrombocytopenic purpura
- vasculitis
- 2-10 yo

HSP

23

what is diagnostic for HSP?

palpable purpura

24

are the palpable purpura from HSP symmetric or asymmetric?

symmetric

25

what are a few GI complications from HSP?

- intussusception
- bleeding

26

what are the renal complications in HSP?

- nephritis (asymptomatic hematuria, possible proteinuria)
- HTN
- progressive renal failure (rare)
- acute insufficiency (rare)

27

what is the treatment for HSP?

- supportive
- steroids (mostly for ab pain)

28

what is the triad of HUS?

- microangiopathic hemolytic anemia
- thrombocytopenia
- renal insufficiency

29

most cases of HUS are caused by:

shiga toxin producing straings E. coli 0157:H7

30

- abdominal pain followed by diarrhea that becomes bloody
- possible fever (low grade)
- petechia
- oliguria
- fatigue, pallor
- edema / HTN
- seizure / coma

HUS

31

what meds should be AVOIDED in HUS?

- antimotility
- abx
- platelet transfusions

32

what is cure / treatment for HUS?

- NO cure!!
- symptomatic care and watchful waiting
- PREVENTION