Rabies virus

Question 1

Two types of rabies virus

Answer 1

Street virus

Fixed virus

Question 2

Characters of fixed virus

Answer 2

Shorter incubation period
No negri bodies
Less pathogenic
No affinity towards salivary gland

Question 3

Cell line for rabies virus

Answer 3

BHK 21

Murine neuroblastoma

Question 4

Pathogenesis of rabies virus

Answer 4

Attack peripheral nerves through nerve endings or sensory motor end plates

Neuronal infection and dysfunction causes
Limbic system affected

Coma depression