Rad L7: CPPD, HADD, Gout Flashcards Preview

CHI303:clinical Science And Diagnosis > Rad L7: CPPD, HADD, Gout > Flashcards

Flashcards in Rad L7: CPPD, HADD, Gout Deck (17):
1

At what age can you get Calcium Pyrophosphate Dyhidrate Deposition Disease (CPPD)?

Peak incidence

  • onset after 30yrs
  • Peak incidence: at 60yrs

2

What are some other diseases that CPPD can simulate?

  • gout
  • RA
  • DJD
  • Charcot's joint

3

What joints are predominantly affected in CPPD?

Peripheral joints

4

What would a positive lab test for CPPD show?

CPPD crystals on aspiration

5

List some possible DDx for CPPD?

W - ilsons disease

H - yperthyroidism

I - diopathic

P - seudo-gout

A - cromagaly, Amyloidosis

D - iapetes

O - chranosis

G - out

6

What is the age/gender predelection of Hydroxyapetite Deposition Disease (HADD)?

M=F

40-70yrs

7

What are some clinical features of HADD?

  • tendonitis
  • bursitis,
  • joint pain
  • tenderness
  • swelling

8

What joints does HADD affect?

  • m.c = Shoulder (supraspinatus tendon) rotator cuff  
  • Also hips and Cervical Spine



 

9

What occurs at the site of crystal deposition (HADD)?

Tissue death

10

What is the Etiology of HADD?

  • Etiology unknown
  • Possibly: Genetic, age, biomechanics, trauma

11

What is Gout?

"rich mans disease" It occurs due to a purine metabolism disorder, in which purine produced >excreted

uric acid thus deposits as Tophus

12

What body region does Gout affect?

  • m.c involves feet
  • primarily periarticular

13

What is the age/gender/demographic predelection to Gout?

  • M>F 20:1
  • >40yrs at time of onset. 
  • Demographic: post menopause patients on diuretics

Family history common

14

What clinical features are evident during the initial onset of Gout?

And what happens if it becomes chronic?

  • Initial onset: Can be asymptomatic, but usually very acute and painful.
  • Chronic: becomes polyarticular

15

What are the clinical features of Gout during the Acute Phase (First phase)?

  • Attack usually early morning
  • 60% at 1st MTP joint
  • Swollen, hot but dry, rapid recovery in days
  • Many pts. are asymptomatic for years

16

What are the clinical features of Gout during the Polyarticular Phase (second phase)?

  • Multiple attacks increase chance of >1 joint involvement
  • This stage is where radiographic changes are first seen

17

What are the clinical features of Gout during the Chronic Tophaceous Phase (third phase)?

  • Tophi now unusual due to drugs (colchicine)
  • Tophi seen after several attacks over many years (10-12 yrs after initial attack)
  • Tophi seen in synovium, cartilage, ligaments, subchondral bone