Random 2 Flashcards

1
Q

What is koebnerisation?

A

koebnerisation or the Koebner phenomenon occurs when new skin lesions occur on sites of previous trauma (e.g. scratches, stings or bites)

occurs in psoriasis (can also occur in vitiligo)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Cabergoline MoA

A

DA agonist

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Octreotide MoA

A

somatostatin analogue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Which airway device can protect the airway from gastric contents?

A

only the tracheal tube can seal the trachea off and protect against aspiration

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

screening test for haemochromatosis

A

transferrin saturation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Fasting before surgery

A

2h for clear liquids
6h for solids

-> Standard national guidelines for elective patients with no
problems affecting gastric emptying. Too long a period of fasting is
unnecessary whilst residual solid food in the stomach poses a big risk ofaspiration/asphyxiation.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

define discrimination

A

Discrimination is the unjust or prejudicial treatment of different categories of people.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Which test has the highest specificity for RA?

A

anti-CCP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Malaria with cerebral involvement - subtype?

A

Cerebral involvement makes falciparum more likely.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Which malaria parasite causes the most severe disease?

A

Plasmodium falciparum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

anastamotic leak post surgery timeframe

A

would happen soon after surgery

-> if a patient is presenting with symptoms months later, this is most likely not the cause

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

maintainance fluid in someone with cardiac disease

A

20-25 ml/kg/24h

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

management of delirium

A
  1. Identify and manage possible underlying causes; effective communication and reorientation
  2. if agitated: try verbal de-escalation; low dose haloperidol is first line medication
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Myasthenia gravis - how to monitor respiratory function?

A

FVC

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

first line initial treatment of sinus bradycardia

A

atropine IV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

A 62 year old man develops acute pain, redness, swelling and warmth of his
right first metatarsophalangeal joint. He has a history of gout and
hypertension. His medications are allopurinol, amlodipine and ramipril.
His eGFR is >60 mL/min/1.73 m2
(>60).

Which is the most appropriate next step in his management?
A. Change allopurinol to febuxostat
B. Start naproxen
C. Stop allopurinol
D. Stop amlodipine
E. Stop ramipril

A

B

The patient has acute gout. The immediate
management would be to commence an NSAID.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Commonest organism in leg cellulitis

A

Streptococcus is the most common pathogen
in leg cellulitis (including in patients with diabetes).
-> strep pyogenes mainly

less commonly:
- staph A
- Pasteurella multocida

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Main lymphatic drainage of the ovary?

A

para-aortic nodes

The iliac nodes are less frequently involved.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Presentation of uveitis

A

red eye
headache
visual disturbance
small pupil
pupil may be irregular
photophobia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

How long does it take for prothrombin complex concentrate to reverse the anticoagulant effects of warfarin?

A

in minutes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Asystole - which med?

A

adrenline

the only recommended medication in asystole

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

What medication should all patients with metallic heart valves be on?

A

aspirin + warfarin

LMWH may be used for bridging

at the moment there is no place for DOACs (yet)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

What would be the reason for normal sats in an unwell patients after a housefire?

A

carboxyhaemoglobin

Co bound to Hb

(affinity of CO is 200x that of O2)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

stain in haemochromatosis

A

(Perl’s) Prussian blue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
What is a boxers fracture?
break in the neck of the 5th metacarpal
26
describe a BCC describe a SCC
BCC: pearly, rolled edges, ulceration, telangiectasia, pigmentation SCC: firm, flesh coloured keratotic papules or plaques, smooth nodules, thick cutaneous horn and ulceration (faster growing)
27
describe eczema herpeticum
- different than normal eczema - circular, depressed, ulcerated lesions - eroded - monomorphic punched out erosions 1-3 mm diameter -> manage with aciclovir (children should be admitted for IV aciclovir)
28
Mx of airway burns
intubate ASAP! this is because pts with burns damage to their airway can develop oedema very rapidly which is life threatening
29
constant leaking of urine spot dx
vesicovaginal fistula
30
Which substance is the primary factor facilitating platelet adhesoin?
Von Willebrand factor
31
What is the commonest complication of meningitis ?
sensorineural hearing loss
32
Oxybutynin MoA
competitive ACh R antagonist -> anitmuscarinic
33
damage of which nerve causes winging of the scapula?
long thoracic nerve
34
sx of axillary nerve damage
- loss of sensation over the deltoid area (patch) - pain - shoulder weakness (esp. when lifting arm up)
35
What electrolyte abnormality is seen in TURP syndrome?
hyponatraemia
36
Features of alcoholic cardiomyopathy
- dilated cardiomyopathy (could cause MR) - can have pancytopenia (Past Paper Question)
37
Features of Morton's neuroma
associated with athletes, tight footwear neuroma between 3rd and 4th toe is the commonest causes sharp burning pain in the ball of the foot thickening of the tissue around one of the nerves leading to your toes
38
Charcot's triad
RUQ pain fever jaundice -> ascending cholangitis
39
What does the SMA supply?
midgut -> from the major duodenal papilla (of the duodenum) to the proximal 2/3 of the transverse colon
40
lower back pain, not related to movement, normal MSK exam... next Ix?
USS could be a AAA
41
Herceptin fancy name
trastuzumab
42
hydatid of Morgagni
small embryological remnant at the upper pole of the testis. (Torsion of the hydatid is of no consequence in itself except that it presents a similar picture to torsion of the testis which is a surgical emergency)
43
SJS vs TEN
now thought to be variants of the same condition it is a rare, unpredictable reaction to medication - SJS: Stevens Johnson syndrome skin detachment <10% BSA - TEN: toxic epidermal necrolysis skin detachment >10% BSA (or >30% BSA ) Detachment between 10% and 30% of BSA is also known as SJS/TEN overlap syndrome S comes before T in the alphabet so SJS is less surface than TEN
44
large binucleate cells with prominent nuclei dx? What is another name for these cells ?
Hodgkin's lymphoma = Reed Sternberg cells
45
Describe what Reed Sternberg cells look like
large binucleate cells with prominent nuclei
46
What effect do benzodiazepines have on respiratory rate ?
reduce you need a bigger dose but they can suppress the RR (sometimes they are used to intubate people)
47
Faget's sign
relative bradycardia with fever seen in typhoid fever
48
Management of BPH
1st line: alpha blocker 2nd line: 5 alpha reductase inhibitor Surgical options include TURP
49
where is a thyroglossal cyst found?
midline
50
what is a cystic hygroma?
birth defect that appears as a sac-like structure with a thin wall that most commonly occurs in the head and neck area of an infant.
51
First line abx in cholera
doxycycline
52
Which common drug should you avoid when taking clarithromycin?
statins -> can accumulate
53
Summarise the different stages of clinical trials
0: exploratory studies, very small number of participants and aim to assess how a drug behaves in the human body. I: safety assessment (determines SE prior to larger studies, conducted on healthy volunteers) II: assess efficacy; involves a small number of patients affected by a particular disease. IIa is for optimal dosing and IIb for efficacy assessment III: new treatment compared with current treatment, involves 100s- 1000s people often as part of a RCT IV: Postmarketing surveillance (monitors for long-term effectiveness and SE)
54
smear cells diagnosis
CLL
55
medication that decreases the amount of urinary protein
ACE-i
56
management of amoebiasis / entamoeba histolytica
oral metronidazole also agent for intraluminal cysts (diloxanide furoate) (the disease can range from asymptomatic to mild diarrhoea to entamoebic dysentery)
57
commonest complication of meningitis
SN hearing loss
58
abx for meningitis
intravenous ceftriaxone but use cefotaxime if administering calcium- containing infusions.
59
statin adjustments with muscle pain and raised CK
> 5x ULN -> stop <5x ULN -> reduce
60
Mx of PE in severe renal impairment (eGFR <15/min)
LMWH instead of DOAC (double check this at MDT)
61
what is erythema multiforme associated with?
herpes simplex MYCOPLASMA PNEUMONIAE fungal infections
62
complications of mycoplasma pneumoniae
erythema multiforme cold AIHA (cold agglutinins IgM may cause haemolytic anaemia/thrombocytopaenia) can also lead to meningitis, pericarditis, myocarditis, hepatitis, pancreatitis, acute glomerulonephritis, bullous myringitis (tympanic membrane)
63
Management of SBP
IV cefotaxime also offer prophylactic oral ciprofloxacin or norfloxacin in people with cirrhosis and ascites with protein 15g/L or less until ascites has resolved
64
features of WPW on ECG
short PRi slurred upstroke of QRS (delta wave) widened QRS b
65
management of WPW
definitive: radiofrequency ablation of the accessory pathway medical: amiodarone, flecainide, sotalol** **avoid if pt also has AF
66
Name an LTRA
montelukast
67
tiotropium drug class
LAMA long acting muscarinic antagonist
68
Which electrolyte abnormalitites do you see in refeeding syndrome?
hypophosphataemia hypokalaemia hypomagnesaemia (may predispose to torsades de pointes)
69
What causes U waves on ECG? How are they described?
small deflection immediately following the T-wave most common: severe hypokalaemia, bradycardia but also: hypocalcaemia, hypomagnesaemia, hypothermia, raised ICP....
70
Barthel index
score done after stroke to assess ability to do ADLs, how dependent/independent someone is
71
score for risk of pressure ulcers
waterlow
72
meds for focal seizures
lamotrigine o levetiracetam are 1st line second line: carbamazepine, oxcarbezepine or zonisaide
73
meds for generalised tonic clonic seizures
male: sodium valproate female: lamotrigine or levetiracetam
74
Which CCBs should be used in angina?
rate limiting e.g. diltiazem or verapamil (if used as monotherapy) if used in combination with a beta blocker, then use a longer acting dihydropyridine CCB like amlodipine or MR nifedipine
75
Which CCBs are ND and dihyrdopyridine?
ND: diltiazem, verapamil (rate limiting) D: amlodipine, nifedipine
76
Which cardiac marker rises 1st after MI?
myoglobin (rises after 30 minutes)
77
Management of BV in pregnancy
oral metronidazole BV increases the risk of preterm labour, low birth weight, chorioamnionitis and late miscarriage -> treat!
78
Bacteria described as curved rod - dx and mx?
campylobacter give clarithromycin
79
Management of normal pressure hydrocephalus
ventriculoperitoneal shunting 10% of pts with shunts expereince significant complications such as seizures, infection and intracerebral haemorrhgaes.
80
CK in PMR
normal
81
MS hypersensitivity type
IV (cell mediated)
82
Abx for prostatitis
ciprofloxacin (or another quinolone)
83
Tamsulosin drug class
alpha blocker
84
finasteride drug class
5 alpha reductase inhibitor
85
Mx of acute closed angle glaucoma
- eye drops (direct parasymphatomimetic e.g. pilocarpine), beta blocker (e.g. timolol) and alpha 2 agonist (e.g. apraclonidine) - IV acetazolamide (reduces aqueous secretions) - some guidelines use topical steroids to reduce inflammation - Laser irridiotomy is the DEFINITIVE management
86
mx of PE in a hemodynamically unstable patient
thrombolysis
87
rash in adults incl palms and soles with lymphadenopathy - likely to be syphilis
syphilis
88
mx of chlamydia in pregnancy
azithromycin 1g stat is the drug of choice can also use erythromycin or amoxicillin discuss the benefits and risks of the treatment with the patient
89
Which fungus most commonly causes athletes foot?
fungi from the genus trichophyton
90
1st line mx of athletes foot
topical terbinafine or imidazole or undecenoate
91
which nerve is responsible for wrist extension and finger extension?
radial nerve
92
motor function of median nerve
pronation of the forearm flexion of the wrist flexion of the digits
93
motor function of the ulnar nerve
majority of intrinsic hand muscles anterior forearm: flexes the ring and little fingers at the DIP flexes and adducts the hand at the wrist
94
Sx of parietal lobe seizures
paraesthesia
95
sx of occipital lobe seizures
floaters/flashes
96
frontal lobe seizure sx
head/leg movements posturing post-ictal weakness (Todd's paresis) Jacksonian march
97
temporal lobe seizure signs
may be with or without impaired awareness aura occurs in most patients (this is actually a focal seizure that then progresses to a generalised seizure in tonic clonic - fun fact) - seizures usually last around 1 min - automatisms (e.g. lip smacking, grabbing, plucking) are common
98
status epilepticus - what do you give if IV loraz 2x did not suffice?
IV phenytoin
99
First line for myoclonic seizures in females
levetiracetam (taM -> Myoclonic)
100
first line for tonic/atonic seizuers in females
lamotrigine AmoT - A/T
101
Which medication for absence seizures?
ethosuxamide (in males and females) AbsencE -> ethosuxamide
102
acute alcohol intake and risk of hepatotoxicity in paracetamol OD
interestingly, acute alcohol intake reduces the risk of hepatotoxicity chronic alcohol intake increases the risk
103
male with focal seizures mx
lamotrigine or levetiracetam both in males and females
104
Summarise anti-epileptic mx in males and females
Males: Sodium valproate for everything except: - focal: lamotrigine/levetiracetam - absence: ethosuxamide Females: lamotrigine/levetiracetam for everything except: - absence: ethosuxamide - in myoclonic levetiracetam > lamotrigine - in tonic /atonic LevetiAceTam > lamotrigine
105
What is juvenile myoclonic epilespy?
classically associated with seizures in the morning or following sleep deprivation typically affects teenage girls and includes a combination of absence seizures, generalised tonic clonic seizures and myoclonic seizures
106
stopping antiepileptic meds
can be considered if seizure free for >2y and done over 2-3 months
107
features of acute interstitial nephritis
fever rash arthralgia eosinophilia mild renal impairment HTN
108
causes of acute interstitial nephritis
1. Drugs (commonest!) - penicillin - rifampicin - NSAIDs - allopurinol - furosemide Systemic disease (SLE, sarcoidosis, Sjogrens) Infection (Hanta virus, staphylococci)
109
Haemolytic uraemic syndrome
generally seen in young children triad: - AKI - microangiopathic haemolytic anaemia - thrombocytopaenia E coli 0157:H7 is the textbook cause other causes: - HIV infection - pneumococca linfection - rare: SLE, drugs, cancer mx: supportive (plasma exchange in severe cases)
110
What is the commonest site of pressure ulcers?
sacrum
111
Which fluid avoid in acidosis?
saline more acidic than Hartmann's
112
vocal resonance in empyema and pneumonia
reduced in empyema increased in pneumonia
113
Features of Vitamin B12 deficiency
macrocytic anaemia sore tongue and mouth neurological disorders - loss of proprioception and vibration sensation - distal paraesthesia mood disturbance you see the neuro features more in B12 than in folate deficiency
114
drug induced interstitial nephritis - when after abx do you get it?
it is rare! would not appear before 4-7 days of abx exposure
115
classic location for venous ulcers
medial and lateral malleolus
116
features of nephrotic syndrome
hypoalbuminaemia proteinuria oedema hypercholesterolaemia
117
Urine sodium clinical significance
useful to differentiate renal vs extrarenal cases of sodium loss in hypovolaemic hyponatraemia Values >20mmol/L -> suggest renal sodium loss. Useful to help confirm SIADH (>40mmol/L)
118
zolendronate route of administration
IV only reserved for those who do not tolerate oral bisphosphonates
119
what causes flashes in retinal detatchment
the separating vitreous will tug on the surface of the retina and create a mechanical depolarization of the axons running through the nerve fiber layer of the retina -> this leads to flashing lights
120
What is atelectasis
common post op complication basal alveolar collapse can lead to respiratory difficulty caused when airways become obstructed by bronchial secretions presents as dyspnoea about 72h post op -> upright positioning and chest PT to manage
121
management of SBO due to adhesions
drip and suck - conservative management 1. IV fluids + NG tube this is successful in 65-80% pts if not successful, get surgeons involved IV abx are NOT indicated in cases managed conservatively
122
blood test findings in DIC
thrombocytopenia prolonged PT and APTT low plasma fibrinogen elevated D-dimer may have microangiopathic abnormalities on blood smear
123
Why cricoid pressure pre intubation?
to prevent gastric contents in a patient who is not fasted or has abdominal problems from passing higher up and obstructing the airway
124
pericardial effusion on ECG
low voltage complexes on ECG
125
risks of exercising despite exertional chest tightness
indicates a high likelihood if IHD vigorous exercise runs the risk of a significant ischaemic event e.g. MI or arrythmia
126
dose of steroid in malignant spinal cord compression
16 mg IV dexamethasone followed by 8 mg BD
127
how to differentiate lithium toxicity from neuroleptic malignant syndrome?
lithium toxicity: - confusion - coarse tremor - jerking leg movements -> may be precipitated by dehydration secondary to D&V NMS: - fever - rigors - autonomic lability (HTN, tachycardia, tachypnoea) - agitated delirium with confusion
128
management of primary biliary cirrhosis
1. ursodeoxycholic acid (increased elimination of retained bile acids and reduces toxicity) 2. colchicine or methotrexate can be used in pts who don't respond to UDCA also manage sx : - pruritus (e.g. colestyramine) - metabolic bone disease: calcium and vit D - portal HTN: b-blockers, banding of varices, TIPS Liver transplant in end stage
129
who gets PBC?
middle aged women most commonly 9:1 (f:m) associated with other AI diseases, may have Sjogrens, Raynauds, arthritis
129
sx of PBC which ix?
fatigue, may have no signs later: jaundice, pale stool, dark urine, hepatomegaly, xanthomas, ascites, signs of liver disease may be found incidentally on bloods with - raised ALP - raised cholesterol AMA-M2 +ve liver biopsy to diagnose
130
pathophys of PBC with PSC
PBC: inflammation and progressive destruction of the small and medium intrahepatic bile ducts leading to chronic cholestasis -> cirrhosis -> most commonly in middle aged women (9:1) -> AMA-M3 PSC: progressive inflammation and fibrosis of intrahepatic and extrahepatic bile ducts -> more common in males (2:1), associated with UC -> associated with increased risk of cancer (cholangiocarcinoma) -> pANCA
131
Mx of PSC
- no curative treatment -sx control: e.g. cholestryramine for pruritus, fat soluble vitamins for deificiency, calcium and vit D, - UDCA may be used (but evidence not as strong as for PSC) - stenting to relieve obstruction - liver transplantation for end stage disease
132
+ve markers in - PSC - PBC - AIH
PSC: p-ANCA PBC: AMA-M2 AIH type 1: SMA, ANA AIH type 2: LKM1, ALC1
133
meds in VT/VF alongside defib
adrenline 1mg amiodarone 300 mg IV
134
pt with fall and head injury, on DOAC, GCS14 what next? A. C spine immobilisation B. CXR C. CT head D. IV prothrombin complex E. IV vit K
A. C spine immobilization this is because in trauma patients the sequence is Airway C-spine
135
which TB abx causes red secretions?
rifampicin
136
where are paneth and goblet cells geerally found?
in the small intestine
137
typical ABG in acute T2RF
hypoxaemia CO2 retention acidosis
138
features of post streptococcal glomeruloephritis
7-14 d post strep A infection - haematuria - fatigue - proteinuria (+/- oedema) - headache - malaise - HTN bloods may show a raised anti-streptolysin O titre (confirms recent streptococcal infection) - low C3
139
anion gap formula
(Na+ + K+) - (Cl- + HCO3-) normal is 10-18 mmol/L
140
What investigation for Addisons?
plasma cortisol and ACTH
141
can a pt have septic arthritis with a -ve gram stain?
yes 50% WILL BE POSITIVE
142
key difference cholangitis and cholecystitis
in cholangitis you get jaundice and the cholestatic LFTs and GGT would be up
143
TCA posioning wihtin 30 mins mx?
activated charcoal
144
Pt with T2DM and CKD not controlled on mteformin - which drug should you add ?
Sitagliptin (DPP4 inhibitor) SGLT2 inhibitors are not licensed - however known to be beneficial
145
route of administration of GLP-1 analogues
sc injection (e.g. liraglutide) given weekly or daily
146
When would you repeat U&Es in a Creatinine raise rather than stoppingthe medicatrion?
if the patient has a <30% increase in serum creatinine -> at this level no indication to change treatment, repeat renal function in 2-4 weeks instead
147
what is frozen shoulder?
= adhesive capsulitis presents with dull shoulder pain the pain often disturbs sleep followed by stiffness and loss of shoulder mobility unlikely in pts <40yo or >70yo -> more likely to be rotator cuff tear or glenohumeral OA subacromial bursitis or rotator cuff tendinopathy often complain of activity related symptoms
148
Pt with acute abdomen following abdo surgery - what ix?
CT scan (usually with contrast) this will provide diagnostic information and help plan further management
149
does furosemide help reduce hyperkalaemia?
yes
150
tamoxifen effect on VTE risk
increases VTE risk
151
Horner syndrome
miosis (small pupil) partial ptosis facial anhidrosis results from interruption of the ipsilateral SNS supply to the head, eye and enck most cases are idiopathic but some conditions such as brainstem stroke, carotid dissection and neoplasms are occasionally identified as the cause.
152
APTT and platelets in anti-phospholipid syndrome
paradoxically prolonged + low platelets
153
NNT formula
1/ARR
154
How do you calculate likelihood ratio?
Likelihood ratio for a positive test result = sensitivity / (1 - specificity)
155
alternative to oral metronidazole in BV
topical clindamycin 2%
156
which antibiotic to close contacts of someone with meningitis?
ciprofloxacin oral
157
abx for legionella
Macrolides such as clarithromycin are used to treat Legionella
158
Organisms causing post splenectomy sepsis
Streptococcus pneumoniae Haemophilus influenzae Meningococci
159
Mx of hiccups in palliative care
chlorpromazine or haloperidol
160
good first line anti-emetic for intracranial causes of N&V
Cyclizine is a good first line anti-emetic for intracranial causes of nausea and vomiting
161
which chemo agent causes haaemorrhagic cystitis?
cyclophosphmide
162
Which chemo agent causes lung fibrosis?
bleomycin
163
Which chemo agent that is used in the management of lymphoma causes peripheral neuropathy?
vincristine
164
where in the lung is adenocarcinoma generally?
causes peripheral lesions
165
What causes Hyaline casts in urine?
loop diuretics e.g. furosemide
166
Mx of anterior uveitis
urgent referral to specialist Anterior uveitis is most likely to be treated with a steroid (drops) + cycloplegic (mydriatic) drops
167
Herpes zoster ophthalmicus (HZO)
- reactivation of the varicella-zoster virus in the area supplied by the ophthalmic division of the trigeminal nerve. -> ~10% of case of shingles.
168
What do pilocarpine eye drops do?
CONSTRICT the pupil immediate management of acute angle-closure glaucoma by causing the pupil to constrict allowing for drainage of aqueous humour.
169
Why should contact lens wearers be sent to opthal ASAP with red eye?
Contact lens wearers who present with a red painful eye should be referred to eye casualty to exclude microbial keratitis
170
Summarises the CKD stages
CKD stage GFR range 1 Greater than 90 ml/min, with some sign of kidney damage on other tests (if all the kidney tests* are normal, there is no CKD) 2 60-90 ml/min with some sign of kidney damage (if kidney tests* are normal, there is no CKD) 3a 45-59 ml/min, a moderate reduction in kidney function 3b 30-44 ml/min, a moderate reduction in kidney function 4 15-29 ml/min, a severe reduction in kidney function 5 Less than 15 ml/min, established kidney failure - dialysis or a kidney transplant may be needed
171
Six of gastroparesis
- erratic blood glucose control - bloating - vomiting - early satiety
172
pupil in surgical CN III palsy
dilated (mydriasis)
173
ipratropium drug class
SAMA
174
Examples of LABAs examples of SAMAs
LABA: Formoterol and salmeterol SAMA: ipratropium
175
Which one is Broca which Wernicke and which lobes are they?
Spoken word is heard at the ear. This passes to Wernicke's area in the temporal lobe (near the ear) to comprehend what was said. Once understood, the signal passes along the arcuate fasciculus, before reaching Broca's area. The Broca's area in the frontal lobe (near the mouth) then generates a signal to coordinate the mouth to speak what is thought (fluent speech).
176
Pneumothorax high risk features
- haemodynamic instability - pronounced hypoxia - bilateral pneumothorax - pre-existing pulmonary pathology - >50 years old with significant smoking history - haemothorax
177
Diving and flying after pneumothorax
Diving -> permanently avoid unless had bilateral surgical pleurectomy and has normal lung function and chest CT scan postop. Flying -> absolute contraindication; may fly 2 w post succesful drainage or 1w post check x-ray
178
Which diabetic medication can be used by obese patients who are pre-diabtetic to help lose weight? how is it given?
liraglutide (GLP-1 analogue) -> once daily SC injections
179
medial epicondylitis
- pain and tenderness localised to the medial epicondyle - pain is aggravated by wrist flexion and pronation - symptoms may be accompanied by numbness / tingling in the 4th and 5th finger due to ulnar nerve involvement
180
lateral epicondylitis
- worsening symptoms when the wrist is extended and supinated as the wrist extensors are contracted, aggravating the point of their insertion at the lateral epicondyle of the humerus.
181
Felty's syndrome
splenomegaly + neutropenia in a patient with rheumatoid arthritis.
182
Describe colles fracture
Colles' - Dorsally Displaced Distal radius → Dinner fork Deformity can be caused by FOOSH
183
prevention of seizures in end of life care
buccal midazolam