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Flashcards in Random Stuff 3 Deck (149)
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1

What is the effect of ANG II on bradykinin levels?

Increases breakdown

2

When in gestation does chorionic villus sampling occur? What is the risk associated with this?

-After 10 weeks
-Limb defects

3

The uterine artery is a branch of what artery?

Anterior internal iliac

4

The middle rectal artery contributes blood to what part of the female pelvic anatomy?

uterus and rectum

5

The vaginal artery is a branch of what artery?

Internal iliac

6

What is adenomyosis, and what are the classic exam findings?

Endometriosis within the uterine myometrium, causing an enlarged, boggy uterus

7

What is the DOC for enterococcus?

Ampicillin

8

What is the treatment for newly acquired HBV?

Lamivudine and IFN-alpha

9

What IFN is used in the treatment of Hep B?

IFN-alpha

10

What is the MOA and use of Lamivudine?

-Cytidine analog that inhibits reverse transcription and blocks Hep replication
-Hep B

11

What is the treatment for HCV?

-Ribavirin and pegylated IFN-alpha2

12

What is the MOA and use of ribavirin?

-Guanosine analog
-RSV and Hep C

13

What is the classic side effect of isoniazid administration, beside the peripheral neuropathy from B6 deficiency?

Hepatotoxic

14

What is the HLA haplotype that is associated with DM I?

HLA-DR3

15

What are the four diseases associated with HLA-DR2?

-SLE
-Goodpasture
-MS
-Hay fever

16

What are the teratogenic effects of phenytoin?

-Skull malformations
-Underdeveloped nails and facial features
-MR

17

What are the components of the following mnemonic for Cp450 inducers: Chronic alcoholics Steal Phen-Phen, and Never Refuses Greasy Carbs"?

-Alcohol
-St. John's wort
-Phenytoin
-Phenobarbital
-Nevirapine
-Rifampin
-Carbamazepine

18

What are the components of the following mnemonic for Cp450 inhibitors: A Cute Gentleman Cipped Iced Grapefruit juice Quickly And Kept Munching on Soft Cinnamon Rolls

-Acute alcohol abuse
-Gemfibrozil
-Ciprofloxacin
-Isoniazid
-Grapefruit juice
-Quinidine
-Amiodarone
-Ketoconazole
-Macrolides
-Sulfonamides
-Cimetidine
-Ritonavir

19

What are the substrates for p450 enzymes (always think when outdoors)?

-Anti-epileptics
-Theophylline
-Warfarin
-OCPs

20

Lesions to the left posterior corpus callosum leads to what neurological deficit?

Reading impairment

21

A lesion to the right angular gyrus would produce what symptoms?

Hemineglect

22

Where is Wernicke's area located?

Posterior part of the left superior temporal gyrus

23

Which antiepileptic medication can cause a folate deficiency?

Phenytoin

24

At what rib level on the right side of the rib cage is the horizontal fissure?

4th

25

Where are GLUT-1 transporters found?

-Cortical neurons
-RBCs

26

Where are GLUT-2 transporters expressed?

Pancreatic Beta cells

27

What is the cause of alkaptonuria? Which amino acid is broken down by this pathway?

-Defect in homogentisate 1,2 dioxygenase
-Tyrosine

28

What is the molecular cause of CF?

defective processing from the ER to the golgi, because the protein is retained in the ER

29

What is the role of GP120 and GP41 on AIDS virus?

-CP120 = binds to CXCR4
-CP40 = causes fusion

30

What is the DOC for enterobius vermicularis?

Albendazole, mebendazole or pyrantel pamoate