RCRL - 20 Q Flashcards

1
Q

The most common cause of false-positive anti-D testing is:

A

The deterioration of reagents.

Failure to following manufacturer’s directions

Spontaneous agglutination of red cells due to a positive DAT.

Rouleaux formation.

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2
Q

Which one of the following statements is true?

A

The ABO and Rh gene loci are present on chromosome 9.

A mixed field reaction (double population),is observed between anti-A1 and A2 red cells.

The A1 and A2 subgroups are distinguished serologically with typing reagent extracted from the Ulex europaeus lectin.

Serum of Bombay phenotype individuals (O) will agglutinate group 0 cells but not group A or B red cells.

the true one is

Anti- A and anti-B produced by group B and group A individuals are predominantly IgM molecules.

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3
Q

A patient has the phenotype O, C neg D pos E pos e neg R2R2. If transfused with blood from six individuals of group O , Rh-positive , the patient could theoretically produce the antibody

A

Anti-C

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4
Q

The pattern of inheritance most frequently expressed by blood group genes is:

A

Autosomal codominant.

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5
Q

In the ABO blood group, the mating of which two phenotypes can produce offspring with each of the common four blood types?

A

A and B.

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6
Q

The fundamental purpose of the cross match is to

A

Detect recipient antibodies that are directed against donor red-cell antigens

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7
Q

In a family study, the mother’s red cell genotype is SS and the father’s is ss. What are the possibilities for the genotypes of the children?

A

100% Ss

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8
Q

Which is true of the primary immune response?

A

Antibody may be detected within hours of antigen stimulation.

Antibody is of relatively high titer.

Antibody is predominantly of the IgG class.

the true is

Antibody is of relatively low titer.

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9
Q

An individual has the following ABH genotype: AO, hh. Which of the following antigens would be present on the red cells of this individual?

A

A and O.

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10
Q

The enzyme responsible for conferring H activity on the red cell membrane is:

A

L-fucosyltransferase.

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11
Q
  1. When studying a pedigree it was noted that the trait was transmitted by affected fathers to all of their daughters and none of their sons. The pattern of inheritance of this trait is:
A

X-linked recessive.

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12
Q

If a potential recipient has no clinically significant antibodies and no record of previous antibodies, which of the following applies?

A

The cross match must include 37°C incubation and the anti-human globulin phase of testing.

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