Reactive Leukocyte Disorders Flashcards by Mary Kate Dierks

Q

-defective leukocyte adhesion b/c of mutations in beta chain of CD11/18 integrins

A

leukocyte adhesion deficiency

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Q

-mutation in fucosyl transferase required for synthesis of sialylated oligosaccharide (receptor for selectins)

A

leukocyte adhesion deficiency

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Q

defective oxidative burst

A

chronic granulomatous disease

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Q

defective membrane component, defective oxidative burst

A

X linked CGD (X-men)

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Q

defective cytoplasmic component, defective oxidative burst

A

AR CGD

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Q

decreased MPO-H202 systmem

A

MPO deficiency

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Q

decreased leukocyte function b/c of mutations affecting lysosomal membrane traffic

A

Chediak-Higashi

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