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Flashcards in Receptors & Effects Handout Deck (15):
1

Effects of stimulating this receptor type results in:
-Vasoconstriction of BVs, ureter, arrector pili muscles, bronchioles, seminal tract, and increases saliva production, insulin resistance
-Neuronal effects: appetite suppression and causes NE to decreased glutamergic postsynaptic potentials
-Increases NE
-Excessive stimulation causes orthostatic hypotension

a1 receptors

2

Phenylephrine:
Receptor subtype?
Agonist or antagonist?

a1 agonist

3

HTN meds, Quetiapine, Risperidone:
Sympathetic receptor subtype target?
Agonist or antagonist?

a1 antagonist

4

Name the receptor subtype:
-Located in prefrontal cortex
-located on both presynaptic and postsynaptic cells
-Decreases release of Ach and NE
-Increases epinephrine

a2 receptors

5

Clonidine, guanfacine, concerta, adderal XR:
Name the sympathetic receptor subtype
Agonist or antagonist?

a2 agonist

6

Aripiprazole, clozapine, lurasidone, mirtazapine, olanzapine, paliperidone, risperidone, quetiapine, and ziprasidone:
What sympathetic receptor subtype?
Agonist or antagonist?

a2 antagonists

7

Name the sympathetic receptor subtype:
-Increases HR, cardiac muscle contractility, lipolysis

B1 receptors

8

Dobutamine acts on what receptor subtype?
Agonist or antagonist?

B1 agonist

9

Name the sympathetic receptor subtype:
-Heart muscle contraction
-Bronchiole dilation
-Glycogenolysis
-Inhibit histamine release from mast cells

B2 receptors

10

Salbutamol, Formoterol, and terbutaline act on what sympathetic receptor subtype?
Agonist or antagonist?

B2 agonists

11

Salivation, lacrimation, urination, defecation, GI pain, emesis are d/t agonist effects on what receptor type?

Muscarinic

12

Pilocarpine acts on what receptor type?
Agonist or antagonist?

M agonist

13

Scopolamine, atropine, and diphenhydramine act on what receptor type?
Agonist or antagonist?

M antagonists

14

Succinylcholine, atracurium, and tubocurarine act on what receptor type?
Agonist or antagonist?

Nicotinic antagonist

15

Name the receptor type:
-Stimulation causes weight gain
-Receptors found in tuberomammillary nucleus of hypothalamus
-Receptors found in cortex and neural excitement causes neuronal excitation or wakefulness

H1