Regulation of Glycolysis via Allosteric control Flashcards Preview

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Flashcards in Regulation of Glycolysis via Allosteric control Deck (14):
1

What type of inhibition does ATP have on enzymes of Glycolysis?

feedback inhibition (PFK-1) and product inhibition (PK)

2

Which modulators have a NEGATIVE impact on Glycolysis? Do they increase or decrease enzymatic activity?

ATP, citrate, G6P, acetyl-CoA || decrease activity

3

Which modulators have a POSITIVE impact on Glycolysis?Do they increase or decrease enzymatic activity?

F6P, 2,6-FBP, AMP & ADP || increase activity

4

What type of inhibition does citrate have on enzymes of Glycolysis?

feedback inhibition

5

What type of inhibition does G6P have on enzymes of Glycolysis?

product inhibition

6

What type of inhibition does acetyl-CoA have on enzymes of Glycolysis?

inter-pathway inhibition

7

What type of inhibition does F6P have on enzymes of Glycolysis?

intra-pathway inhibition

8

What type of inhibition does 2,6-FBP have on enzymes of Glycolysis?

activation

9

What type of inhibition does AMP & ADP have on enzymes of Glycolysis?

activation

10

Which modulators decrease the activity of PFK-1?

ATP and citrate

11

Which modulators increase the activity of PFK-1

2,6-FBP and AMP and ADP

12

Which modulators decrease the activity of PK?

ATP and acetyl-CoA

13

Which modulators increase the activity of PK?

F6P and ADP and AMP

14

Which modulators decrease the activity of HK?

G6P