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Flashcards in Renal Deck (9)
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1
Q

Horseho Kidney

A

Seen commonly in Turners syndrome

  • Can cause later uinary tract obstructions and nincreased risk fo stones
  • Also increased risk for wilms tumor
2
Q

Multicystic dysplastic kidney

A
  • Improper communication between the metanephric mesoderm and ureteric bud (Mesonephros) results in impaired formation filled with CT and cysts
  • Usually unilateral and other side hypertrophies to take over
3
Q

Fanconi’s

A

Impaired secretion of anything in PCT can cause problems with renal function

  • Wilsons disease is a common cause
  • Fanconi’s anemia is related to DS break repair
4
Q

Barter

A
  • Defect in K,Cl,Na cotransporter in ascending limb
  • Acts like loop diuretic
  • Leads to hypokalemia, hypercalciuria, alkalosis
5
Q

Gieltmans

A

-Defect in DCT Na/Cl transporter acts like a thiazide diuretic
-Milder hypokalemia with no hypercalciurua
Mild metabolic acidosis

6
Q

Liddle

A

OVeractivity of ENaC channels in CD leads to spironolactone insensitive hypokalemia, HTN (Hypernatremia)

7
Q

RTA 1

A

Defect in acid secretion by alpha intercalated cells

  • Amphoteracin B, analgesic nephropathy
  • Causes an increased urine pH and can lead to formation of calcium phosphate stones
8
Q

RTA 2

A

Defective HCO3 secretion in PCT leads to metabolic acidoss

-There will be no decrease in H secretion in alpha intercalated cells, so urine will remain acidic

9
Q

RTA-4

A

Hypoaldosteronism
Leads to hyperkalemia that impairs ammoniagenesis in the PCT leading to decrease buffering capacity
-urine will still be acidic