Flashcards in Renal Failure Deck (26)
What are clinical abnormalities seen with chronic renal insufficiency?
Dehydration, metabolic acidosis, hypokalemia, uremia, anorexia, Ca/P imbalance, anemia, hypertension
When is diagnosis of chronic renal insufficiency usually made?
Once isosthenuria and azotemia are present
How does polyuria affect the kidneys?
Hypoperfusion and pre-renal azotemia
How can you treat metabolic acidosis assoc. w/chronic renal insufficiency?
Tx not usually needed but can tx w/potassium citrate
What causes uremia assoc. w/chronic renal insufficiency?
Inability to excrete metabolic byproducts leads to buildup in the bloodstream
What might cause anorexia assoc. w/chronic renal insufficiency?
Uremic ulcers and gastritis
What H2-blocker is frequently used to treat gastric ulcers assoc. w/chronic renal insufficiency?
How does increased phosphate further the progression of renal dysfunction?
Excessive PTH secretion, renal osteodystrophy, extraskeletal mineralization
How can Calcitriol therapy help improve therapeutic outcome of chronic renal insufficiency?
Reduces PTH levels
What is a major factor of anemia assoc. w/chronic renal insufficiency?
Inadequate renal erythropoietin production
How do you manage hypertension assoc. w/chronic renal insufficiency?
How does dietary therapy influence the prognosis of a chronic renal insufficiency case?
Prolongs live 2-3x
What is an appropriate diet for a chronic renal insufficiency patient?
Low protein, low phosphorus, high moisture
What may be indicated to treat a chronic renal insufficiency patient with significant anemia that is compromising QoL or necessitating transfusion?
Recombinant human erythropoietin administration
Does anuria occur with acute or chronic renal disease?
Does anemia occur with acute or chronic renal disease?
What diet decreases formation of nitrogenous wastes?
What drug can help palliate hypertension?
Ca channel blocker (amplodipine)
What are sequelae of renal failure?
Cannot make calcitriol, gastric ulcers, 2* hyperPTH
What does the loss of ability to make calcitriol result in clinically?
Chronic weight loss
What measurement necessitates calcitriol supplementeation?
How does renal disease cause gastric ulcers?
Decreases mucosal blood flow and gastric hypersecretion
How does hyperparathyroidism result from renal failure?
PTH upregulated to compensate for incr. P (d/t decr. GFR)
How is USG affected by chronic renal failure?
What is the most common form of chronic renal failure?