Renal MCQS 2022 Flashcards

1
Q

What is a limitation of organic nitrates such as nitroglycerin (GTN)

A

development of tolerance

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2
Q

What happens to the 10 L-arginine-nitric oxide pathway activity in obesity

A

It is reduced

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3
Q

What is the biomarker that is considered the gold-standard for determining oxidative stress in blood or urine.

A

F2-isoprostane or isoprostanes and isoprostane-like compounds, neuroprostanes

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4
Q

After an acute ischaemic (lack of blood flow) myocardial infarct (heart attack), the reflow of the blood to the infarcted area allows the heart to repair but causes a burst of reactive oxygen species in the heart tissue. The main cellular sources of reactive oxygen species in the injured heart after reflow of blood are

A

neutrophils and macrophages

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5
Q

When does Hyperinsulinemia occur

A

early stage type 2

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6
Q

What is a major action insulin

A

stimulating glucose uptake by adipose tissues

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7
Q

What is stage 2 hypertension blood pressure

A

Systolic blood pressure 160 mmHg and diastolic blood pressure 100 mmHg

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8
Q

What hormone profile does Hyperphagia and obesity usually have

A

reduced level of leptin

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9
Q

Where is leptin secreted from

A

Leptin is secreted from adipocytes in proportion to fat mass

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10
Q

What type of hormone is leptin

A

Leptin is an anti-appetite hormone

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11
Q

How is Leptin synthesized and released into blood circulation

A

by adipocytes

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