Renal Phys--> Body fluid compartments Flashcards Preview

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Flashcards in Renal Phys--> Body fluid compartments Deck (15):
1

What is the plasma solute concentration? Less than or greater than expected? why?

280mM
slight less than 300mM because some is bound to albumin

2

What makes up an anion gap?

Na-(Hco3- + Cl-)
- should be around 10-15
- 140-(25+105)= 10

3

What is osmolality?

Total free solute (mM)/Kg of solvent

4

What is osmolarity?

Total free solute (mM)/Liters of solvent

5

What percent of body is made up of water?

60%
55,500mM

6

What is responsible for the oncotic pressure?

Albumin
- about 1.2-1.4mM in solution
-4.5g/100ml
- exhibits 25mmHg

7

What forms the capillary filtration barrier? What interrupts this?

Glycocalyx
TNF interrupts this in makes caps leaky

8

What is the common intracellular solute makeup?

K 140
Po4-40
Cl 20
Lots of protein
Na 10
Mg 10
So4- 20

9

What makes up common extracellular solute?

Na 140
Cl 105
Hco3- 26
Urea- 6
WOA- 6
Glucose 5
K 4
Ca 4
Mg 1
Albumin-1
H2p04- 1

10

What is iso-osmotic?

Any soln that has 300mOsoms which is physiologic
- NS, D5, Lactated ringers

11

What is isotonic?

Any soln that does not change volume of cell
- NS

12

What is isoncotic?

Any soln with 1mM of plasma albumin or 4.5 grams/100ml
Any soln that exibits 25 mmHg to oncotic pressure

13

What makes up NS and 1/2 ns?

150 and 150 Na:Cl in NS
77 and 77 Na:CL in 1/2NS

14

What makes up lactated ringers?

130 na, 109 cl, 4 K, 4 Ca and 28 lactate

15

What is intracellular, interstitial and plasma water percentage?

2/3 intracellular
1/3 extracellular
a. 3/4 of that in interstium
b. 1/4 of that in plasma