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Flashcards in Renal Regulation of Ions Deck (12):
0

What is the normal intracellular concentration of potassium ions?

140 mEQ/L

1

What does increase in the extracellular potassium level do?

Stimulates increase in aldosterone secretion.

2

Where does reabsorption of the potassium ions occur?

In the proximal tubule and the ascending loop of Henle.

3

Where does the secretion of Potassium ions occur?

The late tubule and collecting duct.

4

What stimulated potassium secretion by the principal cells, in the late distal tubule and cortical collecting tubules?

Potassium concentration and aldosterone.

5

What does small changes in potassium concentration cause?

Large changes in aldosterone secretion by adrenals.

6

Increased sodium intake decreases aldosterone secretion and, therefore, potassium excretion:

however, increased sodium intake also increases GFR and decreases proximal tubular reabsorption of sodium

7

What decreases Calcium excretion?

Increased levels PTH, plasma concentration of phosphate, and metabolic acidosis

8

What stimulates the uptake of potassium by cells?

Insulin and aldosterone

9

What results from an excess secretion of aldosterone (conn's syndrome)?

Hypokalemia

10

What results from a deficiency in aldosterone secretion(Addison's disease)?

Hyperkalemia

11

How much calcium is reabsorbed by the kidneys?

Almost all of it.