Respiratory Microbiology

Question 1

Host Defences in the Nasopharynx:

Answer 1

Nasal hairs
Ciliated epithelia
IgA

Question 2

Host Defences in the Oropharynx

Answer 2

Saliva
Sloughing
Cough

Question 3

Gram positive colonisation of URT (3)

Answer 3

strep. pneumonia
strep. pyogenes
staph. aureus

Question 4

Gram neg. colonisation of URT (2)

Answer 4

Haemophilus Influenzae

Moraxella catharalis

Question 5

Common cause of acute epiglottitis

Answer 5

haemophilus influenzae B

Question 6

Treatment of choice for acute epiglottitis

Answer 6

ceftriaxone

Question 7

Ceftriaxone is a…

Answer 7

cephalosporin

Question 8

Cephalosporins are _________ and act by _________

Answer 8

bactericidal and act by inhibiting cell wall synthesis

Question 9

host defences in the conducting airway (4)

Answer 9

mucociliary escalator
cough
AMPs
Cellular and humoral immunity

Question 10

common bacteria in Acute exacerbation of COPD:

Answer 10

haemophilus influenzae
moraxella catarrhalis
strep. pneumoniae

Question 11

1st line treatment in acute exacerbation of COPD

Answer 11

amoxicillin 500mg TDS (5 days)

Question 12

2nd line treatment in acute exacerbation of COPD

Answer 12

doxycycline 200mg D1 > 100mg D2-5