Review II Flashcards Preview

RENAL II Exam 1 > Review II > Flashcards

Flashcards in Review II Deck (41):
1

pupil dilation

alpha1 - radial m. - sympathetic

2

insulin release

inhibition - alpha2
stimulation - beta2

3

renin release

beta1

4

cardiac M

M2

5

botulinum

inhibit ACh release

6

muscarine

quaternary amine
-mushrooms
enter the brain

7

pilocarpine

mAChR agonist
tertiary - readily absorbed

8

cevilemine

mAChR agonist

9

bethanechol

quaternary - poor absorption - little CNS effects
mAChR agonist

10

increased salivary secretion

pilocarpine and cevilemine

both mAChR agonists

11

varenicline

alpha4 beta2 nAChR agonist

smoking cessation

12

smoking cessation

varenicline

nAChR agonist

13

closed angle glaucoma

pilocarpine and pysostigmine

14

urinary retention

bethanechol

15

post operative ileus

bethanechol

16

methacholine

to Dx bronchial airway hyperreactivity

17

edrophonium

reversible inhibition of AChE

quaternary ammonium

18

physostigmine

CNS effects

19

neostigmine

low CNS effects
AChE inhibitor

also has effects at NMJ

20

pralidoxime

AChE reactivator

21

organophosphate poisoning

pralidoxime

22

closed angle glaucoma

physostigmine - AChE inhibitor
pilocarpine - mAChR agonist

23

anticholinergic intoxication

Tx - with physostigmine - AChE inhibitor

crosses BBB

24

cholinergic poisoning

atropine and pralidoxime

atropine - mAChR antagonist
pralidoxime - regenerate AChE

25

prophylaxis for AChE inhibitor poisoning

pyridostigmine
-reduces incapacitation and mortality

26

atropine

mAChR antagonist
-works in CNS

27

ipratropium

mAChR antagonist
-peripheral affects
-quaternary

28

motion sickness

scopolamine

M1 antagonist

29

gastric effects of atropine

only at high doses

30

parkinsons tremor

Tx - antimuscarinic

31

surgical manipulation of organs

atropine
- to block vagal response

32

COPD

ipratropum and tiotropium

blocks PS bronchoconstriction

33

travellers diarrhea

atropine combined with opiod antidiarrheal

34

oxybutynin

m3 selective antagonist

reduce urinary frequency

35

reduce urinary frequency

oxybutynin - M3 selective antagonist

36

atropine poisoning

dry as a bone, blind as a bat, red as a beet, mad as a hatter, hot as a hare

Tx - cholinesterase inhibitors - physostigmine

37

mecamylamine

ganglion blocker

38

ganglion blocking drug effects

enhance sympathetic tone

dilation of pupil (bc PS dominates)

39

rapid onset mushroom poisoning

Tx atropine

40

M1, 3, 5

excitatory

41

M2, 4

inhibitory