REVISION GUIDE GI: STOMACH Flashcards Preview

PHASE 1 REVISION GUIDE > REVISION GUIDE GI: STOMACH > Flashcards

Flashcards in REVISION GUIDE GI: STOMACH Deck (88)
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1

what are the functions of the stomach?

store and mix food
dissolve and continue digestion
regulate emptying into the duodenum
kill microbes
secretion and activation of proteases
secretion of intrinsic factors
lubrication
mucosal protection
produces chyme

2

what are the different cell types that are found in the stomach?

mucous cells
parietal cells
chief cells
ECL cells
G cells
D cells

3

what is the function of mucous cells in the stomach?

produce mucous
produce HCO3-

4

what is the function of parietal cells in the stomach?

produce gastric acid and intrinsic factor

5

what is the function of chief cells in the stomach?

produce pepsinogen and gastric lipase

6

what is the function of ECL cells in the stomach?

release histamine

7

what is the function of G cells in the stomach?

release gastrin, HCl

8

what is the function of D cells in the stomach?

release somatostatin

9

what is the role of the upper stomach?

secretes mucous, HCl and pepsinogen

10

what is the role of the lower stomach?

contains smooth muscle for mixing contents
secretes endocrine molecules such as gastrin

11

what luminal secretions are found in the cardia of the stomach?

mucus
HCO3-

12

what is the role of the cardia of the stomach?

prevention of reflux
allow entry of food
regulates belching

13

what luminal secretions are found in the fundus and body of the stomach?

H+
intrinsic factor
mucus
HCO3-
pepsinogens
lipase

14

what is the role of the fundus of the stomach?

reservoir
tonic force during emptying

15

what luminal secretions are found in the antrum and pylorus of the stomach?

mucus
HCO3-

16

what is the role of the antrum and pylorus of the stomach?

mixing
grinding
sieving
regulation of emptying

17

what is the order of cells found in the epithelium of the stomach?

top:
mucous neck cells
parietal cells
ECL cells
chief cells
D cells
G cells
bottom

18

what is the role of mucus in the stomach?

it forms a physical barrier between the lumen and the epithelium

19

what is the role of bicarbonate in the stomach?

buffers gastric acid to prevent damage to the epithelium

20

what is the role of gastric acid in the stomach?

activates pepsin
kills bacteria

21

what is the role of intrinsic factor in the stomach?

allows vitamin B12 absorption

22

what is the role of histamine in the stomach?

stimulates gastric acid secretion

23

what is the role of pepsin(ogen) in the stomach?

digests proteins

24

what is the role of gastric lipase in the stomach?

digests fats

25

what is the role of somatostatin in the stomach?

inhibits gastric acid secretion

26

what is the role of gastrin in the stomach?

stimulates gastric acid secretion

27

what is the volume of the empty stomach?

50ml

28

what is the volume of a stomach after eating?

approx. 1.5 litres

29

what is receptive relaxation?

it is the stretching of the stomach when eating

30

what is receptive relaxation mediated by?

by the parasympathetic nervous system acting on the enteric nerve plexuses
coordination with afferent inputs from the stomach is controlled by the swallowing centre in the brain