rheumatology Flashcards

1
Q

if patient allergic to aspirin what DMARD should be given with caution

A

sulfalasazine

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2
Q

what arthritis is caused by IBD

A

enteropathic

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3
Q

risk factor for pseudo gout

A

hyperparathyroidism
hypothyroidism

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4
Q

is CRP normal or elevated in systemic lupus erythematosus

A

normal

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5
Q

what antibiotic cannot be prescribed with methotrexate

A

trimethoprim

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6
Q

for acute attacks of gout what do you give

A

colchicine

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7
Q

investigation for ankylosing spondylitis

A

plain radiograph of pelvis

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8
Q

joint aspirate of rheumatoid arthritis

A

high WBC count
polymorphonuclear neutrophils
yellow and cloudy

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9
Q

positive cardiolipin antibody suggest

A

antiphospholipid syndrome

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10
Q

pencil in cup deformity on Xray is suggestive of

A

psoriatic arthritis

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11
Q

what is important to monitor in a patient taking hydroxychloroquine

A

visual acuity - result in severe, permanent retinopathy

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12
Q

low calcium and phosphate
raised ALP
with generalised bone pain and muscle weakness

A

osteomalacia

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13
Q

what is squaring of the thumb a characteristic feature of

A

osteoarthritis

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14
Q

What is the main side effect of bisphosphonates

A

oesophageal restrictions including oesophagitis, ulcers, erosions

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15
Q

What causes eye problems in GCA

A

anterior ischaemic optic neuropathy

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16
Q

What gene for behcets diseases

A

HLA-B51

17
Q

Symptoms of Behçet’s disease

A
  • anterior uveitis
  • oral ulcer
  • genital ulcers
18
Q

Felty’s syndrome

A

rheumatoid arthritis
Splenomegaly
Neutropenia

19
Q

Antiphospholipid syndrome in pregnancy

A

LMWH

20
Q

1st line investigation for GCA

A

ECR

21
Q

what does co-trimoxazole contain

A

trimethoprim
- do not prescribe with methotrexate

22
Q

ankylosing spondylitis features

A

the A’s
- apical fibrosis
- anterior uveitis
- aortic regurgitation
- achilles tendonitis
- AV node block
- amyloidosis

23
Q

children and adolescents, growing lump on posterior aspect of thigh that is painful
onion skin appearance on radiograph =

A

ewings sarcoma

24
Q

what is febuxostat used for

A

gout

25
Q

what is etanercept an example of

A

anti TNF

26
Q

proximal muscle weakness + rash around eyelids (heliotrope rash) =

A

dermatomyositis

27
Q

dermatological finding in Behcets disease

A

erythema nodosum

28
Q

underlying condition in dermatomyositis

A

internal malignancy

29
Q

is there muscle weakness in poly myalgia rheumatica

A

no

30
Q

sunburst pattern on radiograph

A

osteosarcoma

31
Q

what antibodies are associated with drug induced lupus

A

anti histone antibodies

32
Q

best diagnostic test for granulomatosis with polyangitis

A

cANCA

33
Q

what should be checked before starting azathioprine

A

thiopurine methyltransferase deficiency

34
Q

what should be managed before giving bisphosphonates

A

calcium / vit D deficiency

35
Q

what is sausage fingers also described as

A

dactylics
- seen in psoriatic arthritis

36
Q

riddle for reactive arthritis

A

can’t see, can’t pee, can’t climb a tree

37
Q

if getting chemotherapy what are you at increased risk of

A

gout

38
Q

asymmetrical presentation of stiffness that is relieved by exercise is suggestive of

A

psoriatic arthritis rather than rheumatoid

39
Q

initial investigation for systemic lupus erythematosus

A

ANA