Flashcards in Rheumatology Deck (97):
What is rheumatoid factor?
an IgM against IgG Fc
What are tophi?
gout crystals + giant cells
What is podagra?
big toe inflammaiton
What is CREST syndrome?
E: Esophageal dysmotility
What Ab is assoc with CREST?
What diseases have Raynaud's syndrome
What platelet count do most types of vasculitides have?
Which vasculitis has a high platelet count?
Which vasculitis has normal platelet count?
What is osteoarthritis?
pain worse with activity
What is rheumatoid arthritis?
pain worse in morning
What is Still's disease?
What is Pseudogout?
pyrophosphate crystals in knees and wrists
What is gout?
urate crystals in big toe
What is myositis?
1 muscle hurts
What is polymyositis?
>1 muscle weak
What is dermatomyositis?
myositis + rash
What is fibromyalgia?
hurt all the time
11 trigger points
What is polymyalgia rheumatica?
What is SLE (lupus)?
What is scleroderma?
What is Takayasu Arteritis?
pulseless Asian women
What is Polyarteritis Nodosa?
What is Wegner's Granulomatosis?
attacks ENT, lungs, kidney
What is Goodpasture's?
What is Reiter's syndrome?
males that can't see, can't pee, can't climb a tree
What is Sjogren's syndrome?
females that have dry eyes/mouth
What is Behcet's syndrome?
oral and genital ulcers
What is Churg-Strauss?
What is Felty's syndrome?
What is Kawasaki's Disease?
R: rash (palms/soles)
A: aneurysm (coronary artery--> MI in kids)
S: strawberry tongue
H: hot (fever >102 for at least 3 days + cervical lymphadenopathy)
What is the complication of temporal ateritis?
What is another name for temporal arteritis?
giant cell arteritis
How do you diagnose temporal arteritis?
temporal artery biopsy
What is the rule of 60's for temporal arteritis?
60mg prednisone to tx
What condition is assoc with one muscle hurting?
What condition is assoc with several muscles hurting?
What condition is assoc with musle pain plus rash?
What condition is assoc with inflamed muscle insertions?
What condition causes pain of muscle and muscle insertion?
What condition is assoc with shoulder girdle hurting most?
What condition is assoc with visceral cancer?
dermatomyositis (colon cancer)
What condition is assoc with Rifampin, INH, Statins,Prednisone, and hypothyroidism?
What condition is treated with amitriptyline?
What condition is increased in temporal arteritis?
What condition is assoc with multiple trigger points?
What condition is assoc with muscle pain when moving?
What condition is assoc with heliotropic rash?
What condition is assoc with a throbbing temporal headache?
What drugs cause myositis?
What disease causes myositis?
What is the treatment for multiple sclerosis?
#2 blocking immunoglobulins (TNF-beta)
What structure does MS like to attack
medial longitudinal fasciculus--> internuclear opthalmoplegia
What is the diagnosis for a middle aged woman with optic neuritis (eye problem)?
What is the equivalent disease to MS in children
What vasculitis occurs 2 wks after a common cold?
What disease presents as a smoking Jew with necrotizing vasculitis?
What disease has a family history of deafness and cataracts?
What vasculitis has a strawberry tongue?
What vasculitis has fibrin split products?
What vasculitis presents 2 wks after E. coli gastroenteritis?
hemolytic uremic syndrome
What vasculitis presents with fever, thrombocytopenia, and neuro problems?
What vasculitis attacks midsize arteries (particularly in GI and kidney)?
What vasculitis affects the sinuses, lung, and kidney
What vasculitis has linear immunofluorescence on GBM with lung involvement?
What vasculitis has pulmonary infiltrates with eosinophilia?
What glomerulonephritis occurs two weeks after a sore throat?
What vasculitis presents two wks after vaccination?
What disease leads to septic emboli?
subacute bacterial endocarditis
What is the only vasculitis with a normal platelet count?
What is the only vasculitis with a high platelet count?
What is the MCC of death in SLE?
What protein is decreased in all vasculitides?
What cellular response is seen in all vasculitides?
T cells and macrophages
What are the clues for Kawasaki?
rash on palms and soles
cervical lymph nodes
fever>102 for >3days
What are the clues for TTP?
What are the clues for polyarteritis nodosa?
midsized arteries (GI and renal)
associated with Hep B
What are the clues for Churg-Strauss?
What are the clues for SBE?
caused by strep viridens
What are the clues for MPGN I?
tram tracks with C3 nephritic factor in basement membrane
What are the clues for MPGN II?
tram tracks with low complement (dense deposit disease)
What are clues for CREST?
mildest form of scleroderma
What are the clues for scleroderma?
anti-sm muscle Ab
What are clues for progressive systemic sclerosis?
scleroderma with organ involvement
What are clues for rheumatoid arthritis?
worse in morning
What are clues for juvenile rheumatoid arthritis?
arthritis with iridesis
What are clues for Felty's?
RA + leukopenia + splenomegaly
What are clues for Behcet's?
RA + GI ulcers
What are clues for Sjogren's?
RA + dry eyes, dry mouth
What is the vasculitis with GI bleeding, intussusception, and normal platelet count?
What is the vasculitis whose most common cause of sepsis?
What is the most common cause of renal failure in children?
What is the vasculitis with which Hep B is assoc with?
What vasculitis causes pulmonary infiltrate with eosinophilia?
What vasculitis has xerophthalmia and xerostomia?
What is the most common cause of arthritis in a middle aged female?