Rheumatology Flashcards

1
Q

what does seropositive mean

A

positive for rheumatoid factored

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2
Q

which conditions are seropositive

A

rheumatoid, SLE, sjogrens

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3
Q

anti-centromere

A

limited systemic sclerosis (CREST)

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4
Q

anti-Scl-70

A

diffuse systemic sclerosis

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5
Q

Anti-RNP

A

mixed connective tissue disease

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6
Q

Anti-Ro

A

sjogrens and SLE

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7
Q

Anti-jo

A

polymyositis

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8
Q

anti CCP

A

rheumatoid

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9
Q

other than sore back what might someone with ank spond have

A

achilles tendonitis, osteoporosis, anterior uveitis, aortic regurgitation

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10
Q

examination for ank spond

A

schobers test: 10cm above/5cm below dimples

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11
Q

back pain red flags

A

sudden onset, young / elderly, previous cancer, weight loss, night pain, thoracic, leg weakness, saddle anaesthesia, bladder / bowel difficulties

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12
Q

level for cauda equina

A

L4/5

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13
Q

disc herniations usually in what direction

A

posterior

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14
Q

what happened to reflexes in cauda equine

A

lost

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15
Q

most common level for sciatica

A

L5/S1

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16
Q

sciatica; when is pain worst

A

straight leg lift

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17
Q

claudication relieved by leaning forward

A

spinal stenosis

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18
Q

2 tests for carpal tunnel

A

phalnes: wrists flexed for 60 seconds
Tinels: tapping median nerve

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19
Q

carpal tunnel treatment

A

nocturnal wrist splint, steroid injections, surgical release

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20
Q

acute gout treatment

A

NSAIDs, steroid injection, colchicine (slower action)

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21
Q

gout prophylaxis

A

allopurinol with initial NSAID/colchisine cover

22
Q

DIP swellings are called what and seen in what condition

A

heberdens nodes - OA

23
Q

PIP swellings are called and what condition

A

mouchards nodes - OA

24
Q

what is osteomalacia

A

vit D deficiency causing loss of bone mass

25
Q

what electrolyte changes will you see in osteomalacia

A

low calcium and phosphate, high ALP

26
Q

osteomalacia treatment

A

cholecalciferol - Vit D3

27
Q

DEXA T score that indicates osteopenia

A

-1.0 to -2.5

28
Q

DEXA T score that indicates osteoporosis

A

-2.5 or more

29
Q

osteoporosis treatment

A

bisphosphenates (alendronate/alendronic acid)

30
Q

what blood results will suggest pagets

A

normal other than raises ALP (calcium an dphophate is normal coz it is reiterated into bone)

31
Q

risks associated with pagets

A

osteosarcoma

32
Q

bilateral shoulder, neck, pelvic pain with morning stiffness

A

polymyalgia rheumatica

33
Q

what other condition is polymyalgia rheumatic associate with

A

temporal arteritis

34
Q

polymyalgia rheumatic treatment

A

steroids

35
Q

raynauds treatment

A

Nifedipine (calcium channel blocker)

36
Q

erythema nodosum, urethritis, conjunctivitis, arthritis

A

reactive arthritis

37
Q

HLA associated with rheumatoid

A

HLA-DR4/1

38
Q

rheumatoid: symmetrical or not?

A

symmetrical

39
Q

Rheumatoid: stiffness

A

morning stiffness

40
Q

rheumatoid treatment

A

simple analgesics, short-course prednisolone, methotrexate, sulfasalazine
• if not controlled after 6 months consider infliximab; then etanercept, rituximab

41
Q

rheamatoid: investigations

A

anti-CCP

42
Q

parotid swelling, dry eyes, dry mouth

A

sjogrens

43
Q

risk associated with sjogrens

A

lymphoid malignancy

44
Q

difference between polymyositis and polymyalgia rheumatic

A

polymyosisits: muscle weakness, raised muscle enzymes (CPK)
ploymyalgia: Morning stiffness, CPK normal, raised ESR

45
Q

gottrons sigs

A

dermatomyositis - purple-red papular rash over knuckles

46
Q

C-ANCA

A

granulomatosis with polyangiitis (wegners)

47
Q

p-ANCA

A

churg-strauss syndrome

48
Q

anti-acetylcholine receptor antibodies

A

myasthenia gravis

49
Q

what is Churg-Strauss syndrome

A

eosinophilic granulomatosis with polyangitis - medium sized vessel vasculitis

50
Q

what is a heliotrope rash

A

rash usually seen on user eye lids in dermatomyositis