Flashcards in RNA: Another level of gene control in prokaryotes Deck (10):
Another level of gene control in prokaryotes
Gene regulation using RNA molecules in prokaryotes:
Antisense RNA control
Riboswitches that can act as Ribozymes
An RNA molecule (synthesized in vivo or in vitro) with a ribonucleotide sequence that is complementary to part of an mRNA molecule.
Osmolarity conditions affects movement of water across a membrane due to differences in ion concentrations on inside and outside of membrane
____ proteins function as diffusion pores on ____ membrane
OmpF proteins function as diffusion pores on bacterial membrane
Lower OmpF protein....
less diffusion across membrane
Antisense RNA control under high osmolarity:
Lower OmpF protein; less diffusion across membrane
Riboswitch control of translation
A Regulatory Protein binds to the Riboswitch and Stabilizes a Secondary Structure that masks a Ribosome-Binding site.
-----> No translation takes place.
Without the regulatory protein, the riboswitch assumes an alternative secondary structure that makes the ribosome-binding site available
---->Translation takes place.
Can be repressive (like the vitamin B12 example)
the presence of the regulatory protein can cause a secondary structure that permits translation (inductive)