what is the second most common cause of the common cold?
corona virus are responsible for these 2 disease?
what is the clinical presentation of coronavirus?
upper respiratory tract infection
*no fever, cough, sore throat
what cells does coronavirus infect primarily?
epithelial cells of the upper respiratory tract
SARS is usually limited to a travel history of what?
toronto and far eash china
what is the clinical presentation of SARS?
dyspnea and progressive hypoxia
Chest X ray shows patchy distribution of focal interstitial infiltrates
what is another name for rubella?
3 day measles
what is the biology of rubella?
what cells will rubella infect?
what is the progression of infection?
1) it infects upper respiratory tract and spreads to lymph nodes
2) viremia and spread to whole body
why does the rubella virus spread?
because of unvaccination
what is the clinical presentation for rubella?
coryza (runny nose)
conjunctiva (red eyes)
erythematous maculo-papular rash
when does the rubella rash disappear?
how does the erythematous maculo papular rash in rubella appear?
first on face and spreads to trunk
how is rubella prevented?
through vaccine = MMR
what causes this? what is this?
rubella, erythematous maculo papular rash
what can be a complication that can happen with rubella?
congenita rubella syndrome
what is congenital rubella syndrome?
rubella virus crosses placenta when “sero-negative”mother has primary infection.
what determines the seriousness of congenital rubella syndrome?
the time period of infection
what are some of the symptoms seen in congenital rubella syndrome?
thrombocytopenic purpura (blu-berry muffin baby)
what confirms a diagnosis of rubella?
presense of anti-rubella IgM or IgG
what is the biology of Togavirus?
what are the 2 families of togavirus?
how are togavirus transmitted?
what are the 3 viruses in togavirus?
1) EEE, WEE, VEE
3) West Nile
what symptom will EEE, WEE, VEE cause?
what symptom will chikugunya cause?
joint pain and rash
what symptom is seen in west nile virus?
what mosquito causes EEE, WEE, VEE?
what mosquito causes chikugunya?
what mosquito causes west nile?
what is the biology of flavivirus?
it is enveloped single stranded +RNA
how is flavivirus transmitted?
mosquitoes (arthropod borne) and if transfusion of infected blood or transplantation
what is the treatment for yellow fever?
when is arbovirus mostly affecting patients? (when are patients mostly going to be seen with this?)
what is the host for arbovirus? what is important about this?
humans, they are dead end host (once infect human it cannot further spread)
what is the incubation period for EEE (eastern equine encephilitis), WEE (western equine encephilitis), VEE (venezuelan equine encephilitis)?
what is the clinical presentation for EEE, WEE, VEE?
how is EEE, WEE, VEE different from herpes simplex virus?
there are no flu-like symptom preceding the symptoms
how is the recovery for EEE, WEE, VEE?
complete when there is no central nervous system involvement.
what is the clinical presentation for flavivirus?
what is the clinical presentation for dengue 1st time infection?
severe joint pain (1 week duration)
what is the clinical presentatin for dengue haemorragic fever?
muscle and bone pain
what is the clinical presentation for Dengue Haemorrhagic Shock Syndrome?
muscle and bone pain
what is the clinical presentation of yellow fever?
Severe high fever,
GI bleeding (GI) “Black vomit”,
failure of multiple organs.
how is yellow fever prevented?
Attenuated Live-virus vaccine