Rock Minerals Flashcards Preview

GI > Rock Minerals > Flashcards

Flashcards in Rock Minerals Deck (22):
1

What are the trace minerals?

Iron
Zinc
Copper
Manganese
Fluoride
Iodine
Selenium
Molybdenum
Chromium

2

What is the function of fluoride?

Mineralization of bone and teeth

Dental cavities prevention

3

What is the function of chromium?

Enhances insulin effects

4

What are dietary sources of zinc?

Red meats

Seafood

Poultry

Dairy

Zinc-fortified foods

5

What does zinc play a role in?

Gene regulation

Immunity

Wound healing

Growth

Reproduction

6

How is Zinc taken up on the apical side of epithelial cells?

ZIP4 zinc transporter

7

How is zinc exported on basolateral side?

Zinc transporter ZnT

8

Where does intestinal absorption of zinc mostly happen?

Jejunum

9

What are symptoms of zinc deficiency?

Anorexia

Diarrhea

Reduced taste sensitivity

Increased infections

Poor growth

Skin lesions

Birth defects

10

How does zinc toxicity usually happen?

What are common symptoms of zinc excess?

Supplementation

CNS + GI effects, problems with copper absorption

11

How is iodine taken up into epithelial cells?

Sodium-iodide symporter = SLC5A5

12

What are symptoms of iodine deficiency?

Cold intolerance

Weight gain

Sluggishness

Fetus: growth and mental retardation

13

What are symptoms of iodine toxicity?

Goiter (thyroid enlargement)

Metallic taste in mouth

Increased salivation

GI irritation

Skin lesions

14

What are rich dietary sources of selenium?

Seafood

Eggs

Meat

15

How is selenium taken up into cells?

Na-dependent transporter = inorganic Se in duodenum and cecum

Amino acid transporters = organic Se in small intestine

16

How is iodine transported in plasma?

Unbound

17

How is selenium transported in plasma?

Selenoprotein-P

18

How is fluoride transported in plasma?

Unbound

19

What do deficiencies in selenium cause?

Severe def. = Keshan disease

Moderate deficiency associated with cancer risk

20

What are symptoms of selenium toxicity?

N/V

Diarrhea

Skin rash

Hair loss

Brittle nails

21

What can result from high molybdenum?

Inhibition of copper absorption

*can be used to treat wilson disease (excessive Cu in liver)

22

How does toxicity from manganese arise?

Occupational hazards = metal workers

Neuropsychiatric symptoms