Rubin's 19: Gastrointestinal Tract Flashcards Preview

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Flashcards in Rubin's 19: Gastrointestinal Tract Deck (12):

Achalasia is associated with what disease in the tropics?

Chagas disease


Another term for scleroderma is:

Progressive systemis sclerosis


Dx: Multiple small diverticula in the wall of the esophagus

Intramural pseudodiverticulum


Ingestion of strong acids produces what kind of reaction?

Coagulative necrosis in the esophagus --> protective eschar that limits injury and further chemical penetration Dx: chemical esophagitis


Ingestion of strong bases/alkalines produces what kind of reaction?

Liquefactive necrosis with saponification of membrane lipids


Aflatoxin is a well-known:

hepatotoxin, associated with hepatocellular carcinoma


Sliding hiatal hernia is most often associated with:

Reflux esophagitis


Esophageal varices are most often seen in the setting of:

Portal HTN seen in lower third of esophagus


Dx: "Leather bottle" appearance of thickened stomach; no true tumor seen; Extensive fibrosis in the submucosa and muscularis of the stomach wall; Signet ring cells

Linitis plastica (when the entire stomach is involved) - gastric adenocarcinoma Poor prognosis


Dx: Enlarged rugal folds of stomach; Severe loss of plasma proteins including albumin from altered gastric mucosa; in adults - overexpression of TGF-alpha

Menetrier disease aka hyperplastic hypersecretory gastropathy


Dx: Tarry stool; Upper GI pain; Firm, submucosal, ulcerated mass in the stomach; Spindle cells in cytoplasm

GIST - Gastrointestinal stromal tumor derived from pacemaker cells of Cajal


Give the dx: long-standing ulcerative colitis; jaundice; inflammation and obliterative fibrosis of intrahepatic and extrahepatic bile ducts; Beaded biliary tree on radiography

Primary sclerosing cholangitis