Achalasia is associated with what disease in the tropics?
Another term for scleroderma is:
Progressive systemis sclerosis
Dx: Multiple small diverticula in the wall of the esophagus
Ingestion of strong acids produces what kind of reaction?
Coagulative necrosis in the esophagus --> protective eschar that limits injury and further chemical penetration Dx: chemical esophagitis
Ingestion of strong bases/alkalines produces what kind of reaction?
Liquefactive necrosis with saponification of membrane lipids
Aflatoxin is a well-known:
hepatotoxin, associated with hepatocellular carcinoma
Sliding hiatal hernia is most often associated with:
Esophageal varices are most often seen in the setting of:
Portal HTN seen in lower third of esophagus
Dx: "Leather bottle" appearance of thickened stomach; no true tumor seen; Extensive fibrosis in the submucosa and muscularis of the stomach wall; Signet ring cells
Linitis plastica (when the entire stomach is involved) - gastric adenocarcinoma Poor prognosis
Dx: Enlarged rugal folds of stomach; Severe loss of plasma proteins including albumin from altered gastric mucosa; in adults - overexpression of TGF-alpha
Menetrier disease aka hyperplastic hypersecretory gastropathy
Dx: Tarry stool; Upper GI pain; Firm, submucosal, ulcerated mass in the stomach; Spindle cells in cytoplasm
GIST - Gastrointestinal stromal tumor derived from pacemaker cells of Cajal
Give the dx: long-standing ulcerative colitis; jaundice; inflammation and obliterative fibrosis of intrahepatic and extrahepatic bile ducts; Beaded biliary tree on radiography
Primary sclerosing cholangitis