Flashcards in RX immuno Deck (34):
coarse facies, eczema, retained primary teeth, abscesses due to failure to produce?
IL-17 (hyper IgE)
SCID results are failure to produce?
bone marrow transplant, after several week has rash and diarrhea: what immuno cells/factors are cause?
Alloreactive donor T-lymphocytes (GVHD)
IL associated w/ acute phase rxn
IL6 (produced by T-lymph and macrophages)
where in the cell do proteins bind to MHC1
when a T lymphocyte recieves 1st signal MHC but not second, what occurs
GI infections->hyperplasia peyer patches which do what?
take up antigens and present them to B-cells which then secrete IgA
HLA associated with ulcerative colitis
autoimmune disorder of peripheral myelination with muscle weakness in distal lower and ascends symmetrically, curved gram - rods: what bacteria
endotoxin for n. menigitidis
contact dermatitis can have false PDD BC?
both type IV HSR
goodpasture results in what histologically
linear antibody deposition along glomular basement membrane
name inactivated vaccines
Rabies, Influenza (inj), Polio (salk), Hep A (Rest In Peace Always)
TX for Bruton's agammaglobulinemia
TX for infant w/ hemolytic dz
exchange Rh-Pos for Rh neg blood
what are the antigen presenting cells
dendritic cells, macrophages, B-cells
fever, migratory joint pain, chorea, subcutaneous nodules, heart murmur, ddx?
Rheumatic fever from strep
streptococcal antigens is presented on__
MHCII (w/ 2 alpha and two beta chains)
pt w/Leukocyte adhesion def lacks protein ___ for neutrophil migration
tetanus, botulism, hepatitis B, varicella, rabies
tx for myathenia gravis
endrophonium (inhibitor of acetylcholinesterase)
pernicious anemia co-occurs with hashioto thyroiditis is associated with HLA
why can autoimmune gastritis lead to pernicious anemia
antibodies that interfere with parietal cell secretion of intrinsic factor
EBV infects what type of cell
B cells and epithelial cells
Type IV HSR: pt has prior exposure to antigen which trigger the differentiation of ___into___
CD4+ T lymph to T-helper1
pemphigus vulgaris dz against
intracellular jxns bt epidermal cells (desomsomes)
serum transferrin, serum iron, ferritin, (total iron capacity decrease
tingling, numbness of arm, blurry vision, fatigue, decrease sensation of extremities: tx?
Beta-interferon (IFN-B) bc MS
spider angiomas, frequent falls, IgA def; cause?
defect in DNA repair enzymes (ataxia-telangiectasia)
normocytic anemia, ptosis, double vision, muscle fatigue ddx?
mycobacterium leprae is controlled by
Th1 cells which secrete interferon-gamma
recurrent pyogenic infections, ezcema, throbocytopenia what Ig low?
IgM (Wiskott-aldrish syndrome)