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Flashcards in Schizophrenia Deck (14):
1

what is psychosis?

massive disturbance in someone's thought = losing touch with reality

2

schizophrenia

SSO: suggests it is a disease of the brain (somatic problem) , psychotic disorder, loss of contact with reality, hard to distinguish what is real & what isn't
WHO: severe mental disorder characterized by profound disturbances in thinking, affecting language, perception & sense of self

3

positive symptoms

things you would not normally expect to see
short, non-permanent, come and go like episodes

4

types of positive symptoms

hallucinations: false sensory experiences, can be auditory, uncomfortable
delusions: fixed false beliefs that a person holds, even when proved impossible, unclear, fragmented, disconnected
types: control, grandiosity, paranoia, jealousy, erotomania, reference, nihilism, somatic

5

negative symptoms

things that would normally be present, but aren't
long lasting, can be permanent
chronic emotional disturbances

6

types of negative symptoms

blunted affect: non-expressive
anhedonia: inability to experience pleasure
avolition: lack of motivation
alogia: severely reduced speech

7

cognitive/disorganized symptoms

trouble with attention and memory
disorganized speech: hard to express themselves
- derailment = shifting topics
- tangentially = irrelevant responses
- preservation = using the same words repeatedly (word salads)

8

classification of schizophrenia

no way to confirm diagnosis
Hare - new disease from changes in society
Kraeplin - what if these are all these diseases are actually just symptoms?
Bleuler - negative symptoms are more important

9

DSM IV to 5

elimination of subtitles
reliable not valid
must have at least 1 positive symptom

10

schizoaffective disorder

positive symptoms of schizophrenia + mood disturbances
misdiagnosis b/w schizo, BD & depression

11

schizophrenia epidemiology

men and women equally diagnosed
outcome in developing countries much better than those in less developed countries

12

schizophrenia epidemiology - genetic evidence of schizophrenia

average risk of development
- general pop: 1%
- spouses of people w/ it: 2%
- children of one parent w/ it: 7-15%
- offspring of two parents w/ it: 27-47%
- monozygotic twins: 48-50%
some combinations of genes suspected but research is unclear & inconsistent = unable to genetically predict schizophrenia

13

schizophrenia epidemiology- biological/somatic factors

viral infections
birth complications
neuropathology
neurodevelopmental pr generative?
- cannot detect by looking at MRI
the dopamine hypothesis
- symptoms are a product of specific problems of dopamine activity (meds = decrease in dopamine)

14

schizophrenia epidemiology - social factors

the social causation theory: person's schizophrenia is caused buy the social environment they live in
the social drift hypothesis: a person who has it will drift down the social ladder = lose job, live in bad environment etc.
both?