Section 4 - Quiz Questions

Question 1

Match the receptor with the drug whose action is mediated through it

Maropitant

Answer 1

Match the receptor with the drug whose action is mediated through it

Maropitant

Neurokinin-1 Receptor

Question 2

**Match the receptor with the drug whose action is mediated through it **

Apomorphine

Answer 2

Match the receptor with the drug whose action is mediated through it

Apomorphine

Dopamine Receptor

Question 3

Match the receptor with the drug whose action is mediated through it

Loperamide

Answer 3

Match the receptor with the drug whose action is mediated through it

Loperamide

Opioid Receptor

Question 4

Match the receptor with the drug whose action is mediated through it

Ranitidine

Answer 4

Match the receptor with the drug whose action is mediated through it

Ranitidine

H2-Histamine Receptor

Question 5

Match the receptor with the drug whose action is mediated through it

Erythromycin

Answer 5

Match the receptor with the drug whose action is mediated through it

Erythromycin

_Motilin Receptor _

Question 6

Match each clinical problem listed with the diuretic drug most appropriate for treating it

Hyperkalemia

Answer 6

Match each clinical problem listed with the diuretic drug most appropriate for treating it

Hyperkalemia

Furosemide

Question 7

Match each clinical problem listed with the diuretic drug most appropriate for treating it

Glaucoma

Answer 7

Match each clinical problem listed with the diuretic drug most appropriate for treating it

Glaucoma

Acetazolamide

Question 8

Match each clinical problem listed with the diuretic drug most appropriate for treating it

Hyperaldertonism

Answer 8

Match each clinical problem listed with the diuretic drug most appropriate for treating it

Hyperaldertonism

Spironolactone

Question 9

Match each clinical problem listed with the diuretic drug most appropriate for treating it

Hypokalemia in a patient with compromised hepatic function

Answer 9

Match each clinical problem listed with the diuretic drug most appropriate for treating it

Hypokalemia in a patient with compromised hepatic function

Triamtrene

Question 10

Match each clinical problem listed with the diuretic drug most appropriate for treating it

Hypercalciuria (too much Ca2+ in urine)

Answer 10

Match each clinical problem listed with the diuretic drug most appropriate for treating it

Hypercalciuria (too much Ca2+ in urine)

Hydrochlorothiazide

Question 11

**What pulmonary drug uses this mechanism of action? **

Relaxes bronchial smooth muscle by stimulating intracellular cyclic AMP production

Answer 11

What pulmonary drug uses this mechanism of action?

Relaxes bronchial smooth muscle by stimulating intracellular cyclic AMP production

_Clenbuterol _

Question 12

What pulmonary drug uses this mechanism of action?

Relaxes bronchial smooth muscle by preventing breakdown of intracellular cyclic AMP

Answer 12

What pulmonary drug uses this mechanism of action?

Relaxes bronchial smooth muscle by preventing breakdown of intracellular cyclic AMP

Theophylline

Question 13

What pulmonary drug uses this mechanism of action?

Decreases sensitivity of medullary cough center to sensory stimuli from airways

Answer 13

What pulmonary drug uses this mechanism of action?

Decreases sensitivity of medullary cough center to sensory stimuli from airways

Dextromethrophan

Question 14

What pulmonary drug uses this mechanism of action?

Inhibits vagally-mediated broncho-constriction

Answer 14

What pulmonary drug uses this mechanism of action?

Inhibits vagally-mediated broncho-constriction

Glycopyrrolate

Question 15

Which factor determines the minimum alveolar concentration for an inhalant anesthetic drug?

Answer 15

Which factor determines the minimum alveolar concentration for an inhalant anesthetic drug?

Solubility in lipids (oil:water partition coefficient)

Question 16

Which enzymatic activity is inhibited by:

Omeprazole

Answer 16

Which enzymatic activity is inhibited by:

Omeprazole

H+, K+-ATPase

Question 17

Which enzymatic activity is inhibited by:

Digoxin

Answer 17

Which enzymatic activity is inhibited by:

Digoxin

Na+, K+-ATPase

Question 18

Which enzymatic activity is inhibited by:

Phosphodiesterase

Answer 18

Which enzymatic activity is inhibited by:

Phosphodiesterase

Pimobendan?

Question 19

Which enzymatic activity is inhibited by:

Enalapril

Answer 19

Which enzymatic activity is inhibited by:

Enalapril

Angiotensin-converting enzyme

Question 20

Which action of misoprostil (Cytotec) is required for effective ulcer healing?

Answer 20

Which action of misoprostil (Cytotec) is required for effective ulcer healing?

Gastric antisecretory action

Question 21

Which drug would best meet the following therapeutic goal of slowing the progression of congestive heart failure -

Decrease cardiac after-load by reducing arteriolar resistance

Answer 21

Which drug would best meet the following therapeutic goal of slowing the progression of congestive heart failure -

Decrease cardiac after-load by reducing arteriolar resistance

_Enalapril _

Question 22

Which drug would best meet the following therapeutic goal of slowing the progression of congestive heart failure:

Decrease blood volume in order to reduce cardiac pre-load

Answer 22

Which drug would best meet the following therapeutic goal of slowing the progression of congestive heart failure:

Decrease blood volume in order to reduce cardiac pre-load

Furosemide

Question 23

Which drug would best meet the following therapeutic goal of slowing the progression of congestive heart failure:

Increase cardiac contracility

Answer 23

Which drug would best meet the following therapeutic goal of slowing the progression of congestive heart failure:

Increase cardiac contracility

Digoxin

Question 24

Which drug would best meet the following therapeutic goal of slowing the progression of congestive heart failure:

Reduce sympatho-adrenal influences on cardiac function

Answer 24

Which drug would best meet the following therapeutic goal of slowing the progression of congestive heart failure:

Reduce sympatho-adrenal influences on cardiac function

_Carvedilol _

Question 25

**Match the mechanism of action with the most relevant GI drug:** Stimulates serotonin (5-HT) receptors

Answer 25

**Match the mechanism of action with the most relevant GI drug:** ## Footnote Stimulates serotonin (5-HT) receptors **_Cisapride_**

Question 26

**Match the mechanism of action with the most relevant GI drug:** ## Footnote Stimulates motilin receptors

Answer 26

**Match the mechanism of action with the most relevant GI drug:** Stimulates motilin receptors **_Erythromycin_**

Question 27

**Match the mechanism of action with the most relevant GI drug:** Stimulates opioid receptors

Answer 27

**Match the mechanism of action with the most relevant GI drug:** ## Footnote Stimulates opioid receptors **_Loperamide_**

Question 28

**Match the mechanism of action with the most relevant GI drug:** ## Footnote Blocks substance P receptors

Answer 28

**Match the mechanism of action with the most relevant GI drug:** Blocks substance P receptors **_Maropitant_**

Question 29

**Match the mechanism of action with the most relevant GI drug:** Blocks H2-Histamine receptors

Answer 29

**Match the mechanism of action with the most relevant GI drug:** ## Footnote Blocks H2-Histamine receptors **_Famotidine_**

Question 30

**Which drug below has a mechanism of action that is most similar to that of theophylline?**

Answer 30

**Which drug below has a mechanism of action that is most similar to that of theophylline?** Pimobendan (blocks cAMP breakdown)

Question 31

**Which bronchodilator drug raises intracellular cyclic AMP levels by increasing adenylate cyclase activity?**

Answer 31

**Which bronchodilator drug raises intracellular cyclic AMP levels by increasing adenylate cyclase activity?** Albuterol

Question 32

**Which drug is most effective in promoting the healing of gastric ulcers in horses?**

Answer 32

**Which drug is most effective in promoting the healing of gastric ulcers in horses?** Omeprazole (Gastro-Gard)

Question 33

**Which drug decreases the number of sodium channels expressed by renal tubular cells in a dog with hyperaldosteronism?**

Answer 33

**Which drug decreases the number of sodium channels expressed by renal tubular cells in a dog with hyperaldosteronism?** Spironolactone

Question 34

**Which bronchodilating drug has excellent oral bioavailability, but a relatively narrow therapeutic index?**

Answer 34

**Which bronchodilating drug has excellent oral bioavailability, but a relatively narrow therapeutic index?** Theophylline

Question 35

**Which drug is most effective in treating pulmonary edema in a patient with congestive heart failure?**

Answer 35

**Which drug is most effective in treating pulmonary edema in a patient with congestive heart failure?** Furosemide

Question 36

**Which drug produces peripheral vasoconstriction but increases renal blood flow?**

Answer 36

**Which drug produces peripheral vasoconstriction but increases renal blood flow?** Dopamine

Question 37

**Match the diuretic drug with its correct site of action in the nephron:** Acetazolamide

Answer 37

**Match the diuretic drug with its correct site of action in the nephron:** ## Footnote Acetazolamide **_Proximal Tubule_**

Question 38

**Match the diuretic drug with its correct site of action in the nephron:** ## Footnote Furosemide

Answer 38

**Match the diuretic drug with its correct site of action in the nephron:** Furosemide **_Loop of Henle, thick ascending limb _**

Question 39

**Match the diuretic drug with its correct site of action in the nephron:** Hydrochlorothiazide

Answer 39

**Match the diuretic drug with its correct site of action in the nephron:** ## Footnote Hydrochlorothiazide **_Early distal tubule_**

Question 40

**Match the diuretic drug with its correct site of action in the nephron:** ## Footnote Spironolactone

Answer 40

**Match the diuretic drug with its correct site of action in the nephron:** Spironolactone **_Late distale tubule/Collecting duct _**

Question 41

**Acute digitalis toxicity can produce:** (2)

Answer 41

**Acute digitalis toxicity can produce:** 1. Ectopic pacemaker activity in the ventricles 2. Gastrointestinal Disturbances

Question 42

**Which pharmacotherapeutic regimen is reommended for early stage, class II congestive heart failure?**

Answer 42

**Which pharmacotherapeutic regimen is reommended for early stage, class II congestive heart failure?** A mild diuretic agent, like hydrochlorothiazide

Question 43

**_True/False_** **A dog in congestive heart failure that is given furosemide daily for a number of weeks will likely manifest an increased cardiac response to digitalis.**

Answer 43

**_True/False_** ## Footnote A dog in congestive heart failure that is given furosemide daily for a number of weeks will likely manifest an increased cardiac response to digitalis. **TRUE**

Question 44

**Which inhalant anesthetic agent has the lowest MAC value and induces anesthesia with the slowest onset?**

Answer 44

**Which inhalant anesthetic agent has the lowest MAC value and induces anesthesia with the slowest onset?** Methoxyflurane

Question 45

**Which statement is correct regarding the mechanism by which mannitol acts as a diuretic?**

Answer 45

**Which statement is correct regarding the mechanism by which mannitol acts as a diuretic?** It acts as an osmotic stimulus to decrease water reabsorption from the nephron

Question 46

**Which gastrointestinal drug acts as an AGONIST at CNS dopamine receptors?**

Answer 46

**Which gastrointestinal drug acts as an AGONIST at CNS dopamine receptors?** Apomorphine

Question 47

**Which substance below is an example of an osmotic laxative?** Sorbitol Mineral Oil Bisacodyl

Answer 47

**Which substance below is an example of an osmotic laxative?** ## Footnote **_Sorbitol_** Mineral Oil Bisacodyl

Question 48

**Please indicate the main side effect associated with high efficacy natriuretic drug treatment**

Answer 48

**Please indicate the main side effect associated with high efficacy natriuretic drug treatment** Hypokalemic Metabolic Alkalosis