Sem 2 Session 1 - evidence based medicine

Question 1

definition of Evidence Based Medicine

Answer 1

conscientious (searched) , explicit (appraised) and judicious (appropriate) use of current best evidence in making decisions about the care of the patient integrating individual clinical experties which best availible clinical evidence

• patient
• clinical experties
• evidence

Question 2

biological plausibility

Answer 2

• strenghtens the cause for a causual link as it can be demostrated

Question 3

randomised control trails

Answer 3

• help support if mediciations are useful and effective and help make changes in clinical practice
• updates cinical medicine

Question 5

clincial epidemology order of heirachy

Question 6

case controlled studies (6)

Answer 6

prone to bias

selecting cases and controls so hard to make it fair

Question 7

cohort studies (5)

Answer 7

selecting two groups depending on exposure = less bias because you know exposure came before the disease

Question 8

randomised control studies (4)

Answer 8

not always appropriate for all studies so may have to fall back and use epidemiological studies

Question 9

critically appraised articles (3) - systematic reviews (1)

Answer 9

1 - combinidng every single study of interest and then compiling a conclusion or review

Question 10

is it scientifically proven to work?

Answer 10

looks at comparision between old and new mediciation

Question 11

calculating the relative risk of mortality from the medicication

Answer 11

• percentage of people that died using the medicine (x)
• percentage of people that doed using the placebo ( y)
• relative risk of mortality = x/y
• risk difference = x-y
  *

Question 12

what is the relative risk

Answer 12

tells you how many more times likely you are to die

Question 13

number needed to harm

Answer 13

100 / risk difference

= 1 out of this number will die