Serine Protease Activities Flashcards Preview

Clotting Factors > Serine Protease Activities > Flashcards

Flashcards in Serine Protease Activities Deck (11)
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0
Q

Factor XI

A

Activated by factor XIIa

1
Q

Factor XII

A

Binds to exposed collagen, activated by high molecular weight kininogen and kallikrein

2
Q

Factor IX

A

Activated by factor XIa in the presence of Ca2+

3
Q

Factor VII

A

Activated by tissue factor

4
Q

Factor X

A

Activated on surface of platelets, by factor IXa with VIII and VIIa, TF, Ca2+ (tenase complex)

5
Q

Factor II

A

Activated on surface of platelets by Xa, Ca2+ (prothrombinase complex)

6
Q

Factor VIII

A

Cofactor

Activated by thrombin

7
Q

Factor V

A

Cofactors

Activated by thrombin

8
Q

Factor III (TF)

A

Sub endothelial surface receptor and cofactor

9
Q

Factor I

A

Cleaved by thrombin to form fibrin

10
Q

Factor XIII

A

Ca2+ dependent transglutimase

Activated by thrombin