SERO Tumor Marker Class

Question 1

• Estrogen or progesterone receptors CD markers on white blood cells (WBCs)
• Prognosis for hormone therapy in breast cancer
• Clonality and lineage of WBC neoplasms

Answer 1

Cell surface
markers

Question 2

• Thyroglobulin (TG)
• Immunoglobulins (Ig) and Ig light chains (Bence Jones proteins)

Answer 2

Proteins

Question 3

• Well-differentiated papillary or follicular thyroid carcinoma
• Multiple myeloma and lymphoid malignancies

Answer 3

Proteins

Question 4

• Alpha-fetoprotein (AFP)
• Carcinoembryonic antigen (CEA)

Answer 4

Oncofetal antigens

Question 5

Germ cell carcinomas, hepatocellular carcinoma
Colorectal, breast, or lung cancer

Answer 5

Oncofetal antigens

Question 6

Ovarian cancer
Breast cancer
Pancreatic and gastrointestinal cancers

Answer 6

Carbohydrate antigens

Question 7

Prostate-specific antigen (PSA)
Alkaline phosphatase (ALKP)
Neuron-specific enolase

Answer 7

Enzymes and
isoenzymes

Question 8

Prostate cancer
Bone and liver cancer
Neural tissue neoplasms

Answer 8

Enzymes and
isoenzymes

Question 9

Human chorionic gonadotropin (hCG)
Calcitonin
Gastrin

Answer 9

Hormones

Question 10

Germ cell carcinoma, trophoblastic tumors
Medullary thyroid cancer
Pancreatic gastrinoma

Answer 10

Hormones