Seronegative Arthritis

Question 1

Which gene may SA be associated with in 90% cases?

Answer 1

HLA-B27

Question 2

AS clinical features? on x-ray?

Answer 2

inflammatory back pain
limitation of movement in lumbar spine
limitation of chest expansion

bilateral sacroiliitis on x-ray

Question 3

when is AS onset?

Answer 3

second to third decade

Question 4

what are the other features of AS?

Answer 4

peripheral joints
achiles tendonitis
uveitis
aortic incompetence

Question 5

what examination tests for AS? (4)

Answer 5

Cervical rotation
Occiput to wall
Lateral Spinal Flexion
Modified Schober

COLM

Question 6

AS management?

Answer 6

physiotherapy
NSAIDs
DMARDs 
Anti-TNF
Anti-IL17