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Flashcards in Set 6 Deck (60)
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1

MC breast tumor in pre-, peri- and post-menopausal women?

pre = fibroadenoma (benign)
peri = intraductal papilloma (benign, unilateral bloody discharge)
pst = DCIS (+/- discharge)

2

HIV drug causing pancreatitis

didanosine (NRTI)

3

2 diseases associated with angiodysplasia in elderly?

Aortic stenosis (called Heyde's Syndrome)
ESRD

4

obese diabetic with hepatomegaly and transaminitis? a/w? mechanism?

NASH, 2/2 insulin resistance causing increased rate of lipolysis and circulating insulin
a/w obesity, DM2, HLD and TPN

5

Immunocompromised pt with FOCAL neurologic deficits? Findings?

PML --> MRI w/ multiple demyelinating NON-enhancing lesions, no masses effect

6

Anserine Bursitis

anteromedial tibeal swelling/pain, normal xray, negative valgus stress test (vs. MCL injury)

7

HIV drug CLASS causing SJS

NNRTI

8

Dx and 2nd line Tx for lyme disease

Dx = ELISA/WB
Tx = doxcycline 1st, amoxicillin 2nd

9

HIV drug causing liver failure

Nevirapine (NNRTI)

10

Hemorrhage vs. infarct on CT

hemorrhage = HYPERdense
infarct = hypodense

11

Worst type of mutation in NF2, inheritance?

Nonsense mutation (severe variant)
all are AD

12

photophobia, painful red eye, non-reactive mid-dilated pupil? dx, tx?

acute closed-angle glaucoma
dx = tonometry
tx = acetazolamide (decrease pressure) then pilocarpine (relieve obstruction)

13

deformed feet, joint effusions, osteophytes and bone fragments?

Charcot's joint = neurogenic arthropathy 2/2 neuropathy and repeated wt-bearing trauma

14

What happens to levels of ACTH, aldosterone, cortisol and ADH if chronic steroid patient abruptly stops?

central, tertiary adrenal insufficiency
decreased ACTH, cortisol
increased ADH (normally suppressed by cortisol)
normal aldosterone

15

2 risks of tamoxifen use?

VTE
cancer (endometrial CA, uterine sarcoma)

16

Acid-base disturbance in ASA overdose?

mixed respiratory alkalosis and AG metabolic acidosis (NOT a compensatory respiratory alkalosis though!)

17

conjunctivitis in neonate, 3 ddx and how to differentiate

chemical = 1st 24hrs, no pus
gonococcal = 2-5 days with purulence
chlamydia = 5-15 days, less pus

18

When to do EGD in GERD

fail empiric tx OR
**complicated GERD = dysphagia, odynophagia, wt loss, bleeding or iron deficiency

19

3 MCC bacterial rhinosinusitis? tx?

S pneumo, H flu, M catarrhalis
Tx: augmentin

20

6 causes of drug-induced esophagitis

Tetracyclines, ASA/NSAIDs, Alendronate, KCl, Quinidine, Iron

21

urine/serum osmolality in osmotid diuresis

both elevated but urine > serum

22

3 dx features of Wilson's Disease

Increased urinary copper
Decreased ceruloplasmin
Kayser-Fleischer rings on slit lamp eye exam

23

most and least malignant potential regarding colon polyps

Most = sessile, villous adenoma >2.5cm
Least = hamartomatous and hyperplastic (~benign)

24

Iron, TIBC, ferritin, transferrin sat% in anemia of chronic disease

Decreased = iron, TIBC, transferrin, ~transferrin sat%
Increased ferritin

25

OI pathogenesis, PE findings (4)

type 1 collagen disorder
PE = blue sclera, hearing loss, hypermobile joints, dentinogenesis imperfecta

26

Fall on oustretched hand resulting in Positive drop-arm test (can't hold it up)

rotator cuff tear = supraspinatus injury which controls first 15 degrees of abduction

27

Migratory thrombophlebitis indicates? W/u?

aka Trousseau's Syndrome --> indicates likely underlying malignancy MCC adenocarcinoma (pancreas > lung > prostate > gastric)
Dx = CT abdomen

28

Hemolytic anemia + hepatic vein thrombosis, think...pathogenesis?

Paroxysmal nocturnal hemoglobinuria --> ACQUIRED defect in GP1 anchor responsible for CD55/59 anchoring to RBCs to keep from being targeted by complement

29

acute* symmetric, polyarticular arthritis

viral! MCC parvo B19

30

location of axial skeletal involvement in RA

C1-C2 causing isntability +/- subaxial subluxation