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Flashcards in Shit I dont like Deck (14):
1

Test for ACTH

Stimulation:
- CRH
- Metyrapone (increase 11-deoxycortisol)
- Insulin
- Clonidine -> stimulate CRH

Inhibition:
- Dexamethasone (cortisol analoge -> cause negative-feedback on the pituitary)

2

Treatment for hyperthyroidism

Beta blockers (for some patients)

Prophylthiouracile (block T4 to T3 conversion and thyroid peroxidase)

Radioactive iodine 131 can block thyroid secretion temporary?



3

Treatment for hypothyroidism

Levothyroxine

4

Insulin can be used for?

Diabetes treatment and stimulation test for ACTH and GH stimulation

5

Stimulation test for cortisol

Synacthen/ACTH-stimulation

Insulin via ACTH increase?

6

Treatment for Addison's

Fludrocortisone (aldosterone)
Glucocorticoids

7

Treatment for SIADH and DI

Desmopressin stimulate ADH receptors and can be used to treat central DI
Furosemide can be used for nephrogenic one?

Demeclocycline block ADH receptor function. Good for SIADH



8

What blocks cortisol synthesis and what can it be used for?

Metyrapon block cortisol formation -> cause an increase in ACTHH -> 11-deoxycortisol

9

What can be used for prolactin testing?

Bromocriptine -> dopamine agonist -> block PRL

Metoclopramide -> stimulate PRL

TRH -> stimulate PRL

10

GH stimulation and inhibition

Glucose and somatostatin (octreotide)

11

What is the gold standard for testing of aldosterone? which drug can minic aldosterone and inhibit its formation (supression test)?

Adrenal vein sampling
Check aldosterone and renin levels

Fludrocortison
ACE-inhibitors
Salt loading

12

FSH and LH testing

Clomiphene -> FSH and LH

GnRH

13

TSH stimulation test

TRH (also increase PRL)

14

Clonidine is used for?

suppression of adrenaline -> testing for pheochromocytoma (no decrease)